Results 221 to 230 of about 77,670 (298)

Diverse potential of chimeric antigen receptor‐engineered cell therapy: Beyond cancer

Clinical and Translational Medicine, Volume 15, Issue 4, April 2025.
1. In theory, CAR‐engineering therapy can achieve therapeutic effects by targeting cells expressing specific antigens and thereby eliminating or regulating disease‐related cell subpopulations. 2. Although CAR‐engineering therapy is currently only approved for the treatment of cancer, it has also shown potential in non‐tumour diseases. 3.
Lvying Wu, Lingfeng Zhu, Jin Chen
wiley   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Battling COVID-19 leveraging nanobiotechnology: Gold and silver nanoparticle-B-escin conjugates as SARS-CoV-2 inhibitors. [PDF]

Open Life Sci
Zatla I, Boublenza L.
europepmc   +1 more source

Genetically edited human placental organoids cast new light on the role of ACE2. [PDF]

Cell Death Dis
Arthurs AL, Dietrich B, Knöfler M, Lushington CJ, Thomas PQ, Adikusuma F, Williamson JM, Babikha S, Damhuis T, Jankovic-Karasoulos T, Smith MD, Pringle KG, Roberts CT.   +12 more
europepmc   +1 more source

The ANG-(1–7)/ACE2/mas axis in the regulation of nephron function

, 2010
Carlos M. Ferrario, Jasmina Varagić
openalex   +2 more sources

Unlocking New Pharma/Nutraceutical Frontiers With Neuroprotective Properties of Three Hypericum Species: A Study Combination With In Vitro and In Silico Methodologies

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
This study investigates the phytochemical composition and biopharmacological potential of the extracts from three Hypericum species (H. scabrum, H. lysimachioides, and H. uniglandulosum) from Turkey. The results indicate significant therapeutic potential for these extracts, supporting their development as natural agents against oxidative stress ...
Muammer Bahsi, Simonetta Cristina Di Simone, Dimitrina Zheleva‐Dimitrova, Gokhan Zengin, Gaia Cusumano, Giancarlo Angeles Flores, Paola Angelini, Carla Emiliani, Mehmet Veysi Cetiz, Annalisa Chiavaroli, Luigi Menghini, Guistino Orlando, Claudio Ferrante   +12 more
wiley   +1 more source

Neuropilin‐1 as a Neuroinflammatory Entry Factor for SARS‐CoV‐2 Is Attenuated in Vaccinated COVID‐19 Patients: A Case–Control Study

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aim COVID‐19 is caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) as a pandemic infectious disease. So far, it has been known that this virus uses several receptors to enter the host cell, one of which is neuropilin‐1 (NRP1).
Faezeh Hosseini, Abbas Azadmehr, Kiarash Saleki, Mohamadreza Ahmadifard, Morteza Oladnabi, Moein Shirzad, Mostafa Javanian   +6 more
wiley   +1 more source

PLSCR1 suppresses SARS-CoV-2 infection by downregulating cell surface ACE2. [PDF]

J Virol
Ma R, Zhang X, Li R, Dong X, Wang W, Jiang Q, Xiao X, Shi Y, Chen L, Zheng T, Xiang Z, Ren L, Zhou Z, Lei X, Wang J.   +14 more
europepmc   +1 more source

The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs [PDF]

, 2013
Kim Brint Pedersen, Kavaljit H. Chhabra, Van Kim Nguyen, Huijing Xia, Eric Lazartigues   +4 more
openalex   +1 more source

Significance of Neurological Manifestations and Their Association With Clinical Outcomes in Hospitalized COVID‐19 Patients in Bandar Abbas, Iran: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background Neurological manifestations are increasingly recognized in COVID‐19 patients, yet their prevalence and clinical significance remain understudied. This study aimed to determine the incidence and significance of neurological symptoms and their associations with demographic, clinical, and laboratory parameters in hospitalized COVID‐19 ...
Ahmadagha Negahi, Parivash Davoodian, Omid Esmaeili, Reza Nabavi, Niloufar Khatibzade‐Nasari, Mobina Imeri   +5 more
wiley   +1 more source