Results 231 to 240 of about 97,072 (276)

Reduced circulating 20-hydroxyeicosatetraenoic acid and ACE2 in acute coronary syndrome with exploratory cell-based observations. [PDF]

Sci Rep
Čiapienė I, Ivanauskienė A, Kupstytė-Krištaponė N, Lesauskaitė V, Pranevičius R, Šakalytė G, Stanislovaitienė D, Sithole C, Tatarūnas V.   +8 more
europepmc   +1 more source

Human angiotensin‑converting enzyme 2‑specific benzothiazole-based allosteric inhibitor against pan‑sarbecoviruses. [PDF]

Nat Commun
Liu L, Bai J, Zhou R, Ma Y, Zhou D, Yuen TT, Liu W, Lai PM, Yu W, Duan J, Ye J, Liu X, Gong R, Kwan KY, Lee TT, Liu F, Du Z, Wang P, Luo M, Yang D, Sze KH, Chu H, Chen Z, Liu G.   +23 more
europepmc   +1 more source

Cryo-EM analysis of cooperative conformational changes in the SARS-CoV-2 spike protein trimer. [PDF]

IUCrJ
Wang Q, Cholak S, Woollard G, Subramaniam S, Dao Duc K.   +4 more
europepmc   +1 more source

Kozak sequence libraries for systematically characterizing transgenes across expression levels. [PDF]

Nucleic Acids Res
Shukla N, Kamath ND, Snell JC, Bruchez AM, Matreyek KA.   +4 more
europepmc   +1 more source

Circulating ACE2 levels and ACE I/D polymorphism in severe aortic stenosis. [PDF]

Sci Rep
Mercean DB, Budişan L, Pop LA, Berindan-Neagoe I, Pop D, Şerban AM, Melincovici CS, Mihu CM.   +7 more
europepmc   +1 more source

The Role of the Renin-Angiotensin-Aldosterone System in Hypertensive Emergencies. [PDF]

Biomedicines
Minari TP, Cosenso-Martin LN, Uyemura JRR, Santos AMP, Lopes VDS, Franco RF, Vieira-da-Silva MA, Oliveira KA, Almeida MA, Yugar-Toledo JC, Vilela-Martin JF.   +10 more
europepmc   +1 more source

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Bypassing ACE2

Science Signaling, 2023
SARS-CoV-2 binds to a lysosomal transmembrane protein to enter cells independently of ACE2.
openaire   +2 more sources

ACE2 and Diabetic Complications

Current Pharmaceutical Design, 2007
Angiotensin converting enzyme (ACE) is a key enzyme in the renin angiotensin system (RAS) and converts angiotensin (Ang) I to the vasoconstrictor Ang II, which is thought to be responsible for most of the physiological and pathophysiological effects of the RAS.
Rachael G, Dean, Louise M, Burrell
openaire   +2 more sources

Dimeric ACE2-FC Is Equivalent to Monomeric ACE2 in the Surrogate Virus Neutralization Test

Biochemistry (Moscow), 2023
Angiotensin converting enzyme 2 (ACE2) is the main cellular receptor for the dangerous sarbecoviruses SARS-CoV and SARS-CoV-2. Its recombinant extracellular domain is used to monitor the level of the protective humoral immune response to a viral infection or vaccine using a surrogate virus neutralization test (sVNT).
Denis E, Kolesov, Elizaveta A, Gaiamova, Nadezhda A, Orlova, Ivan I, Vorobiev   +3 more
openaire   +2 more sources

Role of ACE2 in COVID-19

Folia Pharmacologica Japonica, 2022
In the renin-angiotensin system (RAS), angiotensin II (AngII) converted by angiotensin converting enzyme (ACE) exerts a strong physiological activity via the AT1 receptor (AT1R). Thus, the ACE-AngII-AT1R axis positively regulates RAS. On the other hand, angiotensin converting enzyme 2 (ACE2) is known to negatively regulate RAS by degrading AngII into ...
openaire   +2 more sources