Exploring the Impact of ACE Inhibition in Immunity and Disease. [PDF]
J Renin Angiotensin Aldosterone Syst, 2022 Oosthuizen D, Sturrock ED.
europepmc +1 more source
Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]
, 2017 The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella +1 more
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ACE Inhibition and Heart Failure [PDF]
Circulation, 1998 To the Editor: The 2 articles by Spinale et al1 2 represent an important contribution by demonstrating that combination therapy with both ACE inhibitors (ACEI) and AT1 angiotensin II (Ang II) receptor blockers provided greater improvement of left ventricular function and isolated myocyte contractile processes than either therapy used alone.
openaire +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Isolation and Activity Analysis of Abalone-Derived ACE/ACE2 Dual-Target Antihypertensive Peptides [PDF]
Shipin KexueObjective: Antihypertensive peptides with both angiotensin-converting enzyme (ACE) inhibitory activity and ACE2 upregulating activity were prepared from abalone muscle, and their action mechanisms were investigated.
LI Meng, ZHANG Jiekai, HE Bilu, WENG Ling, ZHANG Lingjing, SUN Lechang, CAO Minjie
doaj +1 more source
Curcumin Nanoemulsion: Unveiling Cardioprotective Effects via ACE Inhibition and Antioxidant Properties in Hypertensive Rats. [PDF]
Medicina (Kaunas), 2023 Ishaq M +11 more
europepmc +1 more source
Effects of sacubitril/valsartan in the PARADIGM-HF Trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) according to background therapy [PDF]
, 2016 Background—In the PARADIGM-HF trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure), the angiotensin receptor neprilysin inhibitor sacubitril/valsartan was more effective than the ...
Gong, Jianjian +11 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FoodsIn order to further realize the resource reuse of walnut meal after oil extraction, walnut meal was used as raw material to prepare polypeptide, and its angiotensin-converting enzyme (ACE) inhibitory activity was investigated. The ACE inhibitory peptides
Meng Meng +7 more
doaj +1 more source
Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD. [PDF]
J Hum Hypertens, 2023 Lopez R, Copeland T, McCulloch C, Ku E.
europepmc +1 more source