Results 101 to 110 of about 69,918 (298)
ACE Inhibition and Heart Failure [PDF]
Circulation, 1998 To the Editor: The 2 articles by Spinale et al1 2 represent an important contribution by demonstrating that combination therapy with both ACE inhibitors (ACEI) and AT1 angiotensin II (Ang II) receptor blockers provided greater improvement of left ventricular function and isolated myocyte contractile processes than either therapy used alone.
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Isolation and Activity Analysis of Abalone-Derived ACE/ACE2 Dual-Target Antihypertensive Peptides [PDF]
Shipin KexueObjective: Antihypertensive peptides with both angiotensin-converting enzyme (ACE) inhibitory activity and ACE2 upregulating activity were prepared from abalone muscle, and their action mechanisms were investigated.
LI Meng, ZHANG Jiekai, HE Bilu, WENG Ling, ZHANG Lingjing, SUN Lechang, CAO Minjie
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FoodsIn order to further realize the resource reuse of walnut meal after oil extraction, walnut meal was used as raw material to prepare polypeptide, and its angiotensin-converting enzyme (ACE) inhibitory activity was investigated. The ACE inhibitory peptides
Meng Meng +7 more
doaj +1 more source
Preparation of an ACE-inhibitory peptide from Perinereis aibuhitensis protein
Biotechnology & Biotechnological Equipment, 2017 The peptides with angiotensin-I converting enzyme (ACE)-inhibition activity were prepared from Perinereis aibuhitensis protein (PAP) by hydrolysis with neutral protease, in which the ACE-inhibition rate of peptides derived from PAP was monitored.
Li Chen, Shujun Wang
doaj +1 more source
Curcumin Nanoemulsion: Unveiling Cardioprotective Effects via ACE Inhibition and Antioxidant Properties in Hypertensive Rats. [PDF]
Medicina (Kaunas), 2023 Ishaq M +11 more
europepmc +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD. [PDF]
J Hum Hypertens, 2023 Lopez R, Copeland T, McCulloch C, Ku E.
europepmc +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source