Results 81 to 90 of about 65,941 (263)

Isolation and Activity Analysis of Abalone-Derived ACE/ACE2 Dual-Target Antihypertensive Peptides [PDF]

open access: yesShipin Kexue
Objective: Antihypertensive peptides with both angiotensin-converting enzyme (ACE) inhibitory activity and ACE2 upregulating activity were prepared from abalone muscle, and their action mechanisms were investigated.
LI Meng, ZHANG Jiekai, HE Bilu, WENG Ling, ZHANG Lingjing, SUN Lechang, CAO Minjie
doaj   +1 more source

Curcumin Nanoemulsion: Unveiling Cardioprotective Effects via ACE Inhibition and Antioxidant Properties in Hypertensive Rats. [PDF]

open access: yesMedicina (Kaunas), 2023
Ishaq M   +11 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Optimization of Extraction Process and Activity of Angiotensin-Converting Enzyme (ACE) Inhibitory Peptide from Walnut Meal

open access: yesFoods
In order to further realize the resource reuse of walnut meal after oil extraction, walnut meal was used as raw material to prepare polypeptide, and its angiotensin-converting enzyme (ACE) inhibitory activity was investigated. The ACE inhibitory peptides
Meng Meng   +7 more
doaj   +1 more source

The antiproteinuric effect of ACE inhibition in renal disease [PDF]

open access: yesPharmacy World & Science, 1993
Proteinuria due to non-steroid-responsive renal disease may be harmful. Firstly, because it may cause a nephrotic syndrome, and, secondly, because it is, like hypertension, associated with an increased risk of progressive renal damage and loss of renal function over the years.
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Preparation of an ACE-inhibitory peptide from Perinereis aibuhitensis protein

open access: yesBiotechnology & Biotechnological Equipment, 2017
The peptides with angiotensin-I converting enzyme (ACE)-inhibition activity were prepared from Perinereis aibuhitensis protein (PAP) by hydrolysis with neutral protease, in which the ACE-inhibition rate of peptides derived from PAP was monitored.
Li Chen, Shujun Wang
doaj   +1 more source

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