Results 81 to 90 of about 1,205,174 (292)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluating molecular mechanism of hypotensive peptides interactions with renin and angiotensin converting enzyme.

open access: yesPLoS ONE, 2014
Our previous study showed that three rapeseed protein-derived peptides (TF, LY and RALP) inhibited the in vitro activities of angiotensin converting enzyme (ACE) and renin.
Rong He, Rotimi E Aluko, Xing-Rong Ju
doaj   +1 more source

ACE inhibition scintigraphy in the management of hypertension in children

open access: yes, 1999
Angiotensin converting enzyme (ACE) inhibition scintirenography was performed to help establish the diagnosis and plan treatment of renovascular hypertension (RVH) in 57 hypertensive pediatric patients, 33 infants and 24 children older than 1 year. In 16
Sfakianakis, G. N   +7 more
core   +1 more source

Mechanism of angiotensin converting enzyme (ACE) inhibition by Syzygium polyanthum wight (WALP.) leaves [PDF]

open access: yes, 2021
Syzygium polyanthum is an ethnomedicinal plant used for the treatment of hypertension. This study investigates its antihypertensive property using angiotensin-converting enzyme (ACE) enzyme inhibition assay.
Omar, Muhammad Nor   +6 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Protein Hydrolysates from Citrullus lanatus Seed: Antiradical and Hydrogen Peroxide-scavenging properties and kinetics of Angiotensin-I converting enzyme inhibition

open access: yesCeylon Journal of Science, 2016
This study investigated the in vitro antihypertensive, antiradical and hydrogen peroxide-scavenging properties of protein hydrolysates from Citrullus lanatus (watermelon) seed (CSPHs) obtained through enzymatic digestion.
R. O. Arise   +3 more
doaj   +1 more source

ACE Inhibition and Heart Failure [PDF]

open access: yesCirculation, 1998
To the Editor: The 2 articles by Spinale et al1 2 represent an important contribution by demonstrating that combination therapy with both ACE inhibitors (ACEI) and AT1 angiotensin II (Ang II) receptor blockers provided greater improvement of left ventricular function and isolated myocyte contractile processes than either therapy used alone.
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Antioxidant and ACE Inhibitory Activity of Enzymatic Hydrolysates from Ruditapes philippinarum

open access: yesMolecules, 2018
Ruditapes philippinarum proteins were hydrolyzed by trypsin, neutrase, and pepsin. The antioxidant activities and ACE inhibitory activity of hydrolysates were analyzed and the antioxidant activities were related to their molecular weight distribution and
Yue Yu   +5 more
doaj   +1 more source

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