Results 11 to 20 of about 1,205,174 (292)

Clinical pharmacology of ACE inhibition

Cardiology, 1989
The radioimmunological determinations of immunoreactive 'angiotensin II' do not truly reflect angiotensin-(1-8)octapeptide levels, and thus cannot provide an accurate reflection of the efficacy of angiotensin-converting enzyme (ACE) inhibition. Elaborate
Brunner HR, Waeber, B., Waeber B, Brunner, H. R., Nussberger J, Nussberger, J.   +5 more
core   +4 more sources

Differential inhibition of plasma versus tissue ACE by utibapril:Biochemical and functional evidence for inhibition of vascular ACE activity

Journal of Cardiovascular Pharmacology, 1997
Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with a proposed tissue-specific inhibitory profile. This implies that at a certain dose, utibapril should be able to inhibit tissue ACE activity without affecting plasma ACE.
Buikema, H, van Gilst, W H, vanGilst, WH, deGraeff, PA, Rooks, G, vanGeel, PP, Pinto, YM, deLangen, CDJ, de Graeff, P A, Pinto, Y M, van Geel, P P, de Langen, Cees D J   +11 more
core   +4 more sources

Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]

, 2002
Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.
Humphries, S.E., Rumley, A., Lowe, G.D., Montgomery, H.E., Sanders, J., Brull, D.J.   +5 more
core   +6 more sources

ACE INHIBITION IN THE 1990s

International Journal of Clinical Practice, 1993
SUMMARYAngiotensin‐converting enzyme (ACE) inhibitors are now widely prescribed for the treatment of hypertension and heart failure. Their increasing popularity is based on impressive results from studies of efficacy in clinical situations and the realisation that they may have advantages over conventional treatment.
S R, Maxwell, M J, Kendall
openaire   +2 more sources

ACE Inhibitory Activity and Functional Group Analysis of SolventPartitioned Fractions of Eleusine indica

Pharmaceutical Sciences and Research, 2020
Eleusine indica Linn. Gaerth or Indian goose grass has been widely used as an alternative natural anti-hypertensive agent. However, the rationale behind this mechanism is still unknown.
Jade Celon Cometa, Liahona Faith Roldan Mancol, Anthony Nalzaro Yen, Joanne Katherine Talens Manlusoc   +3 more
doaj   +1 more source

Structural characterization and angiotensin-converting enzyme (ACE) inhibitory mechanism of Stropharia rugosoannulata mushroom peptides prepared by ultrasound

Ultrasonics Sonochemistry, 2022
To reveal the structural characteristics and angiotensin-converting enzyme (ACE) inhibition mechanism of Stropharia rugosoannulata mushroom peptides prepared by multifrequency ultrasound, the peptide distribution, amino acid sequence composition ...
Wen Li, Wanchao Chen, Haile Ma, Di Wu, Zhong Zhang, Yan Yang   +5 more
doaj   +1 more source

Mechanism & inhibition kinetics of bioassay-guided fractions of Indian medicinal plants and foods as ACE inhibitors

Journal of Traditional and Complementary Medicine, 2019
Hypertension is a becoming a major threat to the world. Angiotensin converting enzyme (ACE) is a key part in the renin angiotensin aldosterone system (RAAS) which control blood pressure.
Mohammad Yaseen Khan, Vimal Kumar
doaj   +1 more source

Optimisation and Characterisation of Novel Angiotensin-Converting Enzyme Inhibitory Peptides Prepared by Double Enzymatic Hydrolysis from Agaricus bisporus Scraps

Foods, 2022
Food-derived hypotensive peptides have attracted attention in the field of active peptide research in recent years. In this study, based on ACE inhibition rate and using the Box–Behnken central combination design principle to optimise the process of ACE ...
Rui Wang, Jianmin Yun, Shujuan Wu, Yang Bi, Fengyun Zhao   +4 more
doaj   +1 more source

Moringa oleifera leaves methanolic extract inhibits angiotensin converting enzyme activity in vitro which ameliorates hypertension

Journal of Advanced Biotechnology and Experimental Therapeutics, 2019
Angiotensin Converting Enzyme (ACE) regulates blood pressure. ACE converts angiotensin I to angiotensin II which binds with its receptors and through a cascade of reactions constrict blood vesels, consequently results in increased blood pressure, called ...
Suraiya Aktar, Plabon Kumar Das, Saharia Yeasmin Asha, Mst. Ayesha Siddika, Farhadul Islam, Jahan Ara Khanam, Md. Abdur Rakib   +6 more
doaj   +1 more source

ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270). [PDF]

PLoS ONE, 2011
OBJECTIVES: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme.
Valerio Garrone Barauna, Luciene Cristina Gastalho Campos, Ayumi Aurea Miyakawa, Jose Eduardo Krieger   +3 more
doaj   +1 more source