Results 11 to 20 of about 69,918 (298)

Mechanism & inhibition kinetics of bioassay-guided fractions of Indian medicinal plants and foods as ACE inhibitors

open access: yesJournal of Traditional and Complementary Medicine, 2019
Hypertension is a becoming a major threat to the world. Angiotensin converting enzyme (ACE) is a key part in the renin angiotensin aldosterone system (RAAS) which control blood pressure.
Mohammad Yaseen Khan, Vimal Kumar
doaj   +2 more sources

Exploring the Impact of ACE Inhibition in Immunity and Disease. [PDF]

open access: yesJ Renin Angiotensin Aldosterone Syst, 2022
Angiotensin-converting enzyme (ACE) is a zinc-dependent dipeptidyl carboxypeptidase and is crucial in the renin-angiotensin-aldosterone system (RAAS) but also implicated in immune regulation.
Oosthuizen D, Sturrock ED.
europepmc   +2 more sources

ACE INHIBITION IN THE 1990s

open access: yesInternational Journal of Clinical Practice, 1993
SUMMARYAngiotensin‐converting enzyme (ACE) inhibitors are now widely prescribed for the treatment of hypertension and heart failure. Their increasing popularity is based on impressive results from studies of efficacy in clinical situations and the realisation that they may have advantages over conventional treatment.
S R, Maxwell, M J, Kendall
openaire   +2 more sources

A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensisn l-converting enzyme (ACE) unlinked to the ACE gene [PDF]

open access: yes, 2008
Background: angiotensin I-converting enzyme (ACE) plays an important role in cardiovascular homeostasis. There is evidence from different ethnic groups that circulating ACE levels are influenced by a quantitative trait locus (QTL) at the ACE gene on ...
Amy Luke   +20 more
core   +1 more source

Structural characterization and angiotensin-converting enzyme (ACE) inhibitory mechanism of Stropharia rugosoannulata mushroom peptides prepared by ultrasound

open access: yesUltrasonics Sonochemistry, 2022
To reveal the structural characteristics and angiotensin-converting enzyme (ACE) inhibition mechanism of Stropharia rugosoannulata mushroom peptides prepared by multifrequency ultrasound, the peptide distribution, amino acid sequence composition ...
Wen Li   +5 more
doaj   +1 more source

Optimisation and Characterisation of Novel Angiotensin-Converting Enzyme Inhibitory Peptides Prepared by Double Enzymatic Hydrolysis from Agaricus bisporus Scraps

open access: yesFoods, 2022
Food-derived hypotensive peptides have attracted attention in the field of active peptide research in recent years. In this study, based on ACE inhibition rate and using the Box–Behnken central combination design principle to optimise the process of ACE ...
Rui Wang   +4 more
doaj   +1 more source

DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]

open access: yes, 2012
The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Eisenmenger, Wolfgang   +22 more
core   +1 more source

Spontaneous Hinge-Bending Motions of Angiotensin I Converting Enzyme: Role in Activation and Inhibition

open access: yesMolecules, 2020
The inhibition of human angiotensin I converting enzyme (ACE) has been regarded as a promising approach for the treatment of hypertension. Despite research attempts over many years, our understanding the mechanisms of activation and inhibition of ACE is ...
Thi Tuong Vy   +3 more
doaj   +1 more source

ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270). [PDF]

open access: yesPLoS ONE, 2011
OBJECTIVES: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme.
Valerio Garrone Barauna   +3 more
doaj   +1 more source

Optimization of Enzymatic Hydrolysis of ACE Inhibitory Peptide from Jujube Kernel

open access: yesShipin gongye ke-ji, 2022
In this experiment, jujube kernel protein was extracted from defatted jujube kernel residue by alkali solution and acid precipitation, taking the inhibition rate of angiotensin converting enzyme (ACE) and degree of hydrolysis as indicators to screen the ...
Liming TAN   +4 more
doaj   +1 more source

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