Results 21 to 30 of about 140,143 (309)
Molecules, 2020 The inhibition of human angiotensin I converting enzyme (ACE) has been regarded as a promising approach for the treatment of hypertension. Despite research attempts over many years, our understanding the mechanisms of activation and inhibition of ACE is ...
Thi Tuong Vy +3 more
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ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270). [PDF]
PLoS ONE, 2011 OBJECTIVES: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme.
Valerio Garrone Barauna +3 more
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Optimization of Enzymatic Hydrolysis of ACE Inhibitory Peptide from Jujube Kernel
Shipin gongye ke-ji, 2022 In this experiment, jujube kernel protein was extracted from defatted jujube kernel residue by alkali solution and acid precipitation, taking the inhibition rate of angiotensin converting enzyme (ACE) and degree of hydrolysis as indicators to screen the ...
Liming TAN +4 more
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Journal of Advanced Biotechnology and Experimental Therapeutics, 2019 Angiotensin Converting Enzyme (ACE) regulates blood pressure. ACE converts angiotensin I to angiotensin II which binds with its receptors and through a cascade of reactions constrict blood vesels, consequently results in increased blood pressure, called ...
Suraiya Aktar +6 more
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Pharmaceutical Sciences and Research, 2020 Eleusine indica Linn. Gaerth or Indian goose grass has been widely used as an alternative natural anti-hypertensive agent. However, the rationale behind this mechanism is still unknown.
Jade Celon Cometa +3 more
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Food Chemistry: Molecular Sciences, 2022 We separated a novel functional peptide IFPPKPKDTL from porcine plasma hydrolysate by chromatography, HPLC, and identified by Q Exactive LC-MS/MS. Results showed that IFPPKPKDTL had a significant ability of ACE inhibition (76.6%) likely due to the ...
Junqi Zhan +3 more
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Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]
, 2013 Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin +13 more
core +4 more sources
Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis [PDF]
, 2018 We sought to decipher the mechanisms underlying the kidney's response to changes in K+ load and intake, under physiological and pathophysiological conditions.
Edwards, Aurelie +2 more
core +1 more source
Characterization of ACE Inhibitory Peptides Prepared from Pyropia pseudolinearis Protein
Marine Drugs, 2021 More than 7000 red algae species have been classified. Although most of them are underused, they are a protein-rich marine resource. The hydrolysates of red algal proteins are good candidates for the inhibition of the angiotensin-I-converting enzyme (ACE)
Yuya Kumagai +7 more
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CyTA - Journal of Food, 2020 The main aim of this study was to transform bovine colostrum into a tribiotic product through a metabolic conversion with a microbial consortium based on artisanal and starter microorganisms.
Mihaela Cotârleţ +4 more
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