Results 31 to 40 of about 1,205,174 (292)

Three Novel ACE Inhibitory Peptides Isolated From Ginkgo biloba Seeds: Purification, Inhibitory Kinetic and Mechanism

Frontiers in Pharmacology, 2019
Alcalase, dispase, trypsin, and flavourzyme were used to hydrolyze the extracted Ginkgo biloba seeds protein isolate (GPI). The Ginkgo protein hydrolyzates (GPHs) with the maximum degree of hydrolysis (DH) and ACE inhibitory activity were selected, and ...
Fei-Fei Ma, Hao Wang, Hao Wang, Chao-Kun Wei, Kiran Thakur, Zhao-Jun Wei, Zhao-Jun Wei, Li Jiang   +7 more
doaj   +1 more source

Effect of tofacitinib therapy on angiotensin converting enzyme activity in rheumatoid arthritis

Frontiers in Medicine, 2023
IntroductionThe Renin-Angiotensin-Aldosterone system (RAAS) has been implicated in the regulation of the cardiovascular system and linked to rheumatoid arthritis (RA).
Dorottya Kacsándi, Miklós Fagyas, Ágnes Horváth, Edit Végh, Anita Pusztai, Monika Czókolyová, Boglárka Soós, Attila Ádám Szabó, Attila Ádám Szabó, Attila Hamar, Zsófia Pethő, Nóra Bodnár, György Kerekes, Katalin Hodosi, Szilvia Szamosi, Gabriella Szűcs, Zoltán Papp, Zoltán Szekanecz   +17 more
doaj   +1 more source

Physical Activity and Inhibition of ACE Additively Modulate ACE/ACE-2 Balance in Heart Failure in Mice [PDF]

, 2021
Angiotensin-converting enzyme inhibition (ACE-I) and physical activity favorably modulate the ACE/ACE-2 balance. However, it is not clear whether physical activity and ACE-I could synergistically modulate ACE/ACE-2 balance in the course of heart failure (
Berkowicz, Piotr, Tyrankiewicz, Urszula, Żołądź, Jerzy, Jablonska, Magdalena, Chłopicki, Stefan, Olkowicz, Mariola, Smolenski, Ryszard T., Mariola Olkowicz, Urszula Tyrankiewicz, Magdalena Jablonska, Stefan Chlopicki, Piotr Berkowicz, Ryszard T. Smolenski, Jerzy A. Zoladz   +13 more
core   +1 more source

Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]

Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس, پناهپور, حمداله   +1 more
core   +1 more source

Tissue ACE inhibition and sodium status in left ventricular dysfunction [PDF]

, 2005
Left ventricular (LV) dysfunction is characterized by a progressive loss of cardiac pump function, which eventually leads to the clinical syndrome of chronic heart failure (CHF). Heart failure is associated with high morbidity and mortality.
Westendorp, Bart
core   +4 more sources

Novel angiotensin-converting enzyme inhibitory peptides from caseins and whey proteins of goat milk

Journal of Advanced Research, 2017
Angiotensin-converting enzyme (ACE) plays a central role in blood pressure regulation by producing the vasoconstrictor angiotensin II. The inhibition of ACE with natural inhibitors, as alternatives to avoid the side effect of synthetic drugs, is a major ...
Hisham R. Ibrahim, Ahmed S. Ahmed, Takeshi Miyata   +2 more
doaj   +1 more source

南瓜籽ACE抑制肽的Plastein反应修饰及分离鉴定Plastein reaction modification of pumpkin seed ACE inhibitory peptide and its isolation and identification

Zhongguo youzhi, 2023
为进一步提升南瓜籽多肽的ACE抑制活性，利用Plastein反应对南瓜籽ACE抑制肽进行修饰，探究底物质量分数、反应温度、反应时间以及3种外源氨基酸添加量对ACE抑制率的影响。采用超滤和Sephadex G-25柱层析等分离修饰产物，并利用LC-MS/MS鉴定肽序列。结果表明：Plastein反应修饰的最佳条件为底物质量分数45%，反应温度20 ℃，反应时间3 h；分别添加亮氨酸、苯丙氨酸或甘氨酸均能显著提升修饰产物的ACE抑制率，其中添加0.5 mmol/g亮氨酸时，修饰产物的ACE抑制率最高 ...
胡田媛1,杨晨1，陈哲2,3，郑竟成1,3，何东平1,3，杨永2,3，雷芬芬1,3 HU Tianyuan1, YANG Chen1, CHEN Zhe2,3, ZHENG Jingcheng1,3, HE Dongping1,3, YANG Yong2,3, LEI Fenfen1,3
doaj   +1 more source

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]

, 2005
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Lee, A.J., Smith Judith A, Lee, Alison J., Shirras Alan D, Shirras, A.D., Smith, Judith A., Isaac, R.E., Shirras, Alan D., Isaac R Elwyn, Burnham Susan, Smith, J.A., Burnham, Susan, Burnham, S., Lee Alison J, Isaac, R. Elwyn   +14 more
core   +5 more sources

Mobola plum seed methanolic extracts exhibit mixed type inhibition of angiotensin Ⅰ-converting enzyme in vitro

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To explore the possible inhibitory potentials and mechanism by Mobola plum (Parinari curatellifolia) seeds crude methanol (CE) and flavonoid-rich (FE) extracts on angiotensin-1-converting enzyme (ACE Ⅰ).
Olamide Olajusi Crown, Olanrewaju Sam Olayeriju, Ayodele Oluwaseyi Kolawole, Afolabi Clement Akinmoladun, Mary Tolulope Olaleye, Afolabi Akintunde Akindahunsi   +5 more
doaj   +1 more source

ACE Inhibitory Peptides Derived from Muscovy Duck (Cairina moschata) Plasma

Foods, 2022
In this study, angiotensin-converting enzyme inhibitory peptides (ACE–IPs) derived from Muscovy duck (Cairina moschata) plasma hydrolysate (MDPH) were investigated.
Zongshuai Zhu, Haoyu Guo, Yan Xu, Anthony Pius Bassey, Ahtisham Ali, Ming Huang, Jichao Huang   +6 more
doaj   +1 more source