Effect of tofacitinib therapy on angiotensin converting enzyme activity in rheumatoid arthritis
Frontiers in Medicine, 2023 IntroductionThe Renin-Angiotensin-Aldosterone system (RAAS) has been implicated in the regulation of the cardiovascular system and linked to rheumatoid arthritis (RA).
Dorottya Kacsándi +17 more
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Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]
, 2002 Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
Hausmann, Dirk +10 more
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The antiproteinuric effect of ace inhibition in renal disease [PDF]
, 1992 In 1985 some studies were published showing that angiotensin converting enzyme (ACE) inhibition not only reduced the elevated blood pressure in animals with chronic renal failure (experimentally induced by renal ablation or by induced diabetic ...
Heeg, J.E., Heeg, Jan Evert,
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Zhongguo youzhi, 2023 为进一步提升南瓜籽多肽的ACE抑制活性，利用Plastein反应对南瓜籽ACE抑制肽进行修饰，探究底物质量分数、反应温度、反应时间以及3种外源氨基酸添加量对ACE抑制率的影响。采用超滤和Sephadex G-25柱层析等分离修饰产物，并利用LC-MS/MS鉴定肽序列。结果表明：Plastein反应修饰的最佳条件为底物质量分数45%，反应温度20 ℃，反应时间3 h；分别添加亮氨酸、苯丙氨酸或甘氨酸均能显著提升修饰产物的ACE抑制率，其中添加0.5 mmol/g亮氨酸时，修饰产物的ACE抑制率最高 ...
胡田媛1,杨晨1，陈哲2,3，郑竟成1,3，何东平1,3，杨永2,3，雷芬芬1,3 HU Tianyuan1, YANG Chen1, CHEN Zhe2,3, ZHENG Jingcheng1,3, HE Dongping1,3, YANG Yong2,3, LEI Fenfen1,3
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Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
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Bradykinin is a mediator of anaphylactoid reactions during hemodialysis with AN69 membranes [PDF]
, 1994 Bradykinin is a mediator of anaphylactoid reactions during hemodialysis with AN69 membranes. Anaphylactoid reactions (AR) are the most feared complications of hemodialysis.
Verresen, Luc +3 more
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ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
, 1997 Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian +6 more
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Neonatal ACE inhibition in rats interferes with lung development [PDF]
, 2004 The renin-angiotensin system (RAS) is developmentally up-regulated and it is essential for kidney development in several species. Given the fact that the rat lung undergoes postnatal development, the mammalian lung possesses the highest angiotensin ...
Chen, Yun, +4 more
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Asian Pacific Journal of Tropical Biomedicine, 2017 Objective: To explore the possible inhibitory potentials and mechanism by Mobola plum (Parinari curatellifolia) seeds crude methanol (CE) and flavonoid-rich (FE) extracts on angiotensin-1-converting enzyme (ACE â ).
Olamide Olajusi Crown +5 more
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Physical Activity and Inhibition of ACE Additively Modulate ACE/ACE-2 Balance in Heart Failure in Mice [PDF]
, 2021 Angiotensin-converting enzyme inhibition (ACE-I) and physical activity favorably modulate the ACE/ACE-2 balance. However, it is not clear whether physical activity and ACE-I could synergistically modulate ACE/ACE-2 balance in the course of heart failure (
Berkowicz, Piotr +6 more
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