Results 51 to 60 of about 65,941 (263)

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Angiotensin converting enzyme (ACE) inhibitors activity from purified compounds Fructus Phaleria macrocarpa (Scheff) Boerl

BMC Complementary Medicine and Therapies, 2023
Background Mahkota Dewa [Phaleria macrocarpa (Scheff) Boerl.] fruit in vitro and in- vivo can decrease and prevent elevation of the blood pressure, lower plasma glucose levels, possess an antioxidant effect, and recover liver and kidney damage in rats ...
Aprilita Rina Yanti Eff, Hasniza Zaman Huri, Maksum Radji, Abdul Mun’im, F. D. Suyatna, Yonatan Eden   +5 more
doaj   +1 more source

Proteinuria in systemic sclerosis: reversal by ACE inhibition [PDF]

Rheumatology International, 2013
In systemic sclerosis (SSc), kidney damage is a major clinical problem which can lead to a deleterious outcome. Recently, in diabetes mellitus, early detection of proteinuria and treatment with angiotensin-converting enzyme (ACE) inhibitors has been shown to slow progression of kidney disease and to improve prognosis. In this study, we investigated the
Schuster, J., Moinzadeh, P., Kurschat, C., Benzing, T., Krieg, T., Weber, M., Hunzelmann, N.   +6 more
openaire   +2 more sources

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez, Kayla Etienne, Long Di, Valerie Martinez‐Torres, Andrew Rosenberg, Sakir H. Gultekin, Aditi Dhir, Bradley Gampel, Heather J. McCrea   +8 more
wiley   +1 more source

Dual platelet inhibition in ACS - The Styrian consensus [PDF]

Cor et Vasa, 2013
AbstractDual antiplatelet therapy facilitated treatment of acute coronary syndromes and enabled the wide use of stents after clopidogrel emerged on the market about twenty years ago. Although this was a milestone in cardiology, clopidogrel inherits several disadvantages which are likely to reduce clinical benefit of its use and a new generation of ...
von Lewinski, Dirk, Schuchlenz, Herwig, Doppler, Reinhard, Wallner, Markus, Pieske, Burkert   +4 more
openaire   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Bradykinin-mediated effects of ACE inhibition

Kidney International, 1992
A 42-year-old black man with a history of essential hypertension was admitted to the Clinical Research Center at the Boston University School of Medicine for participation in a research protocol designed to assess the blood-pressure-lowering effect of the renin inhibitor A-64662 (Abbott Laboratories).
openaire   +2 more sources

Phosphate REINs in the Renoprotective Benefit of ACE Inhibition [PDF]

Journal of the American Society of Nephrology, 2011
Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor antagonists (ARB) attenuate progression of chronic kidney disease (CKD).[1][1],[2][2] Nevertheless, the incidence and prevalence of end-stage renal disease (ESRD) continue to increase despite widespread use of these ...
Geoffrey A, Block, Myles, Wolf
openaire   +2 more sources