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ACE Inhibition in Cardiovascular Disease

New England Journal of Medicine, 2000
An important article in this issue of the Journal describes the results of the Heart Outcomes Prevention Evaluation (HOPE) study, which are likely to have important implications for the treatment o...
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Effects of ACE inhibition on the heart.

Journal of human hypertension, 1995
Inhibition of the angiotensin converting enzyme (ACE) results in suppression of the formation of angiotensin II and delay of the degradation of bradykinin. Hence, the pharmacological effects of ACE inhibitors are attributable to both of these mechanisms.
I, Gavras, A, Manolis, H, Gavras
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Present and future of ACE inhibition

Trends in Pharmacological Sciences, 2002
ACE Inhibitorsedited by P. D'Orleans-Juste and G.E. Plante, Birkhauser Verlag, 2001. Euro119 (hardback) (x + 184 pages) ISBN 376435982XToday, blockers of the renin–angiotensin system are standard therapy for essential hypertension and congestive heart failure, and represent an important step in the management of patients with diabetic and non-diabetic ...
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A decade of angiotensin-converting enzyme (ACE) inhibition

The American Journal of Medicine, 1992
The renin system plays a critical role in hypertension as well as in the edematous states of heart failure, cirrhosis, and nephrosis. Properly performed measurements of plasma renin, with techniques now widely available, can be used as indicators of risk and of therapeutic strategies.
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Effect of ACE inhibition on neurohormones.

European heart journal, 1999
Long-term controlled trials in heart failure in patients with asymptomatic left ventricular dysfunction indicate the potential of ACE inhibition to reduce ischaemic events, such as unstable angina and myocardial infarction. These effects occur after long-term medication and suggest structural rather than functional effects of ACE inhibitors.
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ACE inhibition and renal protection.

Clinical physiology and biochemistry, 1993
In patients with renal disease, altered renal function causes elevation of blood pressure, but hypertension in its turn accelerates progression of renal failure. Lowering of blood pressure into the normotensive range is beneficial for slowing progression.
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ACE inhibition

PharmacoEconomics & Outcomes News, 1996
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Influence of ACE inhibition on insulin resistance

Nephrology Dialysis Transplantation, 1995
R, Dzúrik, V, Spustová, A, Oksa
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