Results 91 to 100 of about 3,024,177 (290)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Evaluation of ACE-inhibitor Induced Laryngeal Edema Using Fiberoptic Scope: A Case Report. [PDF]

J Educ Teach Emerg Med, 2022
Singh J, Danko C.
europepmc   +1 more source

Risk factors associated with severe and recurrent angioedema: An epidemic linked to ACE‐inhibitors [PDF]

, 2014
Patricia A. Loftus, Melin Tan, G. Patel, Juan Lin, Sam Helman, Arvind Badhey, Eugenie Du, Richard V. Smith, Marvin P. Fried, Thomas J. Ow   +9 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Chitosan-Covered Calcium Phosphate Particles Co-Loaded with Superoxide Dismutase 1 and ACE Inhibitor: Development, Characterization and Effect on Intraocular Pressure. [PDF]

Pharmaceutics, 2023
Popova E, Matveeva O, Beznos O, Tikhomirova V, Kudryashova E, Grigoriev Y, Chesnokova N, Kost O.   +7 more
europepmc   +1 more source

ARB users exhibit a lower fracture incidence than ACE inhibitor users among older hypertensive men

Age and Ageing, 2016
T. Kwok, J. Leung, E. Barrett-Connor
semanticscholar   +1 more source

Targeting ACE and ECE with dual acting inhibitors

, 2007
Stephen Hanessian, Sébastien Guesné, Ludivine Riber, Julien Marin, Alain Benoist, Philippe Mennecier, Alain Rupin, Tony J. Verbeuren, Guillaume De Nanteuil   +8 more
openalex   +1 more source

Angiotensin converting enzyme (ACE) inhibitors in the treatment of heart failure in general practice in north Cumbria [PDF]

, 2000
Martin Toal, Robert D. Walker
openalex   +1 more source

Breakthrough: a first-in-class virtual simulator for dose optimization of ACE inhibitors in translational cardiovascular medicine [PDF]

, 2023
Benjamin Schneider, Jessica Ward, Samantha Sotillo, Catherine Garelli‐Paar, Emilie Guillot, Marc Prikazsky, Jonathan P. Mochel   +6 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source