Results 71 to 80 of about 89,590 (297)
Tissue Angiotensin II Generating System by Angiotensin-Converting Enzyme and Chymase
Journal of Pharmacological Sciences, 2006 .: It had been believed that angiotensin II (Ang II) was produced by the renin-angiotensin system (RAS), which was established in the 1950’s. After a while, people realized that the multiple functions of Ang II could not be explained by the conventional ...
Mizuo Miyazaki, Shinji Takai
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The in vivo characterisation of a C-domain specific ACE inhibitor
, 2013 Includes bibliographical references.The ACE protein is a zinc-dependent dipeptidyl carboxypeptidase comprised of two homologous domains termed the C- and N-domain.
Sharp, Sarah-Kate
core
Peripheral artery disease: potential role of ACE-inhibitor therapy
, 2008 Subjects with peripheral arterial disease (PAD) of the lower limbs are at high risk for cardiovascular and cerebrovascular events and the prevalence of coronary artery disease in such patients is elevated.
Rosa Maria Grisanti +9 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2022 Panel A shows the plot for cumulative exposure > 3 years (of exposure to daily high dose or equivalent) in patients with concomitant background ACE-inhibitor treatment. Panel B shows the plot for cumulative exposure ≤ 3 years in patients with concomitant
Ilke Sipahi (12184222)
core +1 more source
ACE inhibitors in patients with acute myocardial infarction
Кардиоваскулярная терапия и профилактика, 2005 The article is devoted to modern perspectives of ACE inhibitor therapy in patients with acute myocardial infarction (AMI). ACE inhibitor efficacy is analyzed, according to the results of large randomized studies.
S. N. Tereshchenko, N. A. Dzhaiani
doaj
FEBS Open Bio, 2015 Angiotensin converting enzyme (ACE) is a zinc‐dependent dipeptidyl carboxypeptidase with an essential role in blood pressure homeostasis in mammals.
Charlotte Harrison, K. Ravi Acharya
doaj +1 more source
Antioxidant and Ace Inhibitor Potential of Stripe Trevally Fish (Selaroides leptolepis) Hydrolysate
Squalen, 2018 This study aimed to investigate the potency of fish protein hydrolysates (FPH) of stripe trevally fish (Selaroides leptolepis) as antioxidant and ACE inhibitor.
Reinal Putalan +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source