Results 61 to 70 of about 87,017 (286)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
ACE inhibitors in patients with acute myocardial infarction
Кардиоваскулярная терапия и профилактика, 2005 The article is devoted to modern perspectives of ACE inhibitor therapy in patients with acute myocardial infarction (AMI). ACE inhibitor efficacy is analyzed, according to the results of large randomized studies.
S. N. Tereshchenko, N. A. Dzhaiani
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Рациональная фармакотерапия в кардиологии, 2016 The possible indications for the choice of two component antihypertensives combinations are presented. The advantages of ACE inhibitor+calcium channel blocker combination are shown in terms of antihypertensive efficacy, organoprotective properties, and ...
O. D. Ostroumova +2 more
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Рациональная фармакотерапия в кардиологии, 2015 Data on the updated approach to the choice of two-component antihypertensive combinations for different clinical situations are presented. Advantages and indications for combination of an angiotensin converting enzyme (ACE) inhibitor and dihydropyridine ...
O. D. Ostroumova, I. I. Kopchenov
doaj +3 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Journal of Advanced Lung HealthIntroduction: Angioedema, particularly when induced by angiotensin-converting enzyme (ACE) inhibitors, represents a significant clinical concern due to its potential severity, including life-threatening airway obstruction.
Sudeep Acharya +12 more
doaj +1 more source
Journal of Tropical Pharmacy and Chemistry, 2016 Penelitian ini bertujuan untuk mengetahui tingkat hidrolisis tanduk muda rusa Sambar (Rusa unicolor) dengan enzim pencernaanm yaitu enzim pepsin dan tripsin, serta mengetahui adanya aktivitas Angiotensin I-Converting Enzyme Inhibitor ...
Arif Ismanto
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source