Results 221 to 230 of about 11,854 (255)

Rational module substitution strategy to enhance ACE-inhibitory peptide activity

Food Chemistry
Food-derived angiotensin-converting enzyme (ACE)-inhibitory peptide plays key roles in hypertension prevention, however, their activity is dependent on specific sequence composition. This study aims to enhance peptide activity using a module substitution strategy.
Qingping, Liang, Siyuan, Peng, Zhemin, Liu, Jia, Wang, Luying, Tang, Changliang, Zhu, Lin, Zhu, Min, Yang, Dongyu, Li, Haijin, Mou   +9 more
openaire   +2 more sources

Revisiting the mechanisms of ACE inhibitory peptides from food proteins

Trends in Food Science & Technology, 2017
Abstract Background Angiotensin converting enzyme (ACE) is a key enzyme in the renin angiotensin system (RAS) responsible for conversion of angiotensin (Ang) I into Ang II, a vasoconstrictor leading to elevated blood pressure. ACE inhibitory (ACEi) peptides derived from food proteins have shown potential in the prevention and management of ...
Jianping Wu, Wang Liao, Chibuike C. Udenigwe   +2 more
openaire   +1 more source

Anxiolytic effects of ACE inhibitory peptides on the behavior of rats in an elevated plus-maze

Food & Function, 2016
Three novel egg white-derived peptides were demonstrated to display in vitro activities against the angiotensin converting enzyme (ACE).
Zhipeng, Yu, Wenzhu, Zhao, Long, Ding, Yiding, Yu, Jingbo, Liu   +4 more
openaire   +2 more sources

LKPNM: a prodrug-type ACE-inhibitory peptide derived from fish protein

Immunopharmacology, 1999
It has been previously documented that the thermolysin-digest of "Katsuo-bushi", a Japanese traditional food processed from dried bonito possesses potent inhibitory activity against angiotensin I-converting enzyme (ACE). The present authors isolated eight kinds of ACE-inhibitory peptides from it.
H, Fujita, M, Yoshikawa
openaire   +2 more sources

Food derived ACE inhibitory peptides

2022
Sujit Das, Subrota Hati
openaire   +1 more source

Identification and mechanistic characterization of novel ACE-inhibitory peptides derived from Nattokinase

Food Chemistry
Hypertension remains a major global health challenge and is associated with increased cardiovascular risk. Angiotensin-converting enzyme (ACE) plays a pivotal role in blood pressure regulation; however, conventional synthetic ACE inhibitors are often accompanied by undesirable side effects.
Siyuan, Peng, QingPing, Liang, Wenjing, Qiao, Yangyang, Han, Haijin, Mou, Min, Yang   +5 more
openaire   +2 more sources

Deepstack-ACE: A deep stacking-based ensemble learning framework for the accelerated discovery of ACE inhibitory peptides

Methods
Identifying angiotensin-I-converting enzyme (ACE) inhibitory peptides accurately is crucial for understanding the primary factor that regulates the renin-angiotensin system and for providing guidance in developing new potential drugs. Given the inherent experimental complexities, using computational methods for in silico peptide identification could be
Phasit, Charoenkwan, Pramote, Chumnanpuen, Nalini, Schaduangrat, Watshara, Shoombuatong   +3 more
openaire   +2 more sources

Predicting variable-length ACE inhibitory peptides based on graph convolutional network

International Journal of Biological Macromolecules
Traditional molecular descriptors have contributed to the prediction of angiotensin I-converting enzyme (ACE) inhibitory peptides, but they often fall short in capturing the complex structure of the molecule. To address these limitations, this study introduces molecular graphs as an advanced method for peptide characterization. Peptides containing 2-10
Yating, Rong, Baolong, Feng, Xiaoshuang, Cai, Hongjie, Song, Lili, Wang, Yehui, Wang, Xinxu, Yan, Yulin, Sun, Jinyong, Zhao, Ping, Li, Huihui, Yang, Yutang, Wang, Fengzhong, Wang   +12 more
openaire   +2 more sources

Identification and molecular interactions of novel ACE inhibitory peptides from rapeseed protein

Food Chemistry, 2023
Guanhao Bu, Fusheng Chen, Xiaojie Duan
exaly  

Purification identification and function analysis of ACE inhibitory peptide from protein

Food Chemistry, 2023
He Hongyan, Tuanjie Che
exaly