Results 131 to 140 of about 82,991 (273)

Serum IGF‐1 and the Risk of Cardio‐Kidney Outcomes in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) increases cardiovascular and kidney disease risk. Insulin‐like growth factor 1 (IGF‐1) regulates metabolic and vascular function, but its role in long‐term cardio‐kidney outcomes (CKO) in MASLD remains unclear.
Yongin Cho, Hye‐Sun Park, Tae Seop Lim, Jong Ho Jhee, Jong Hyun Jhee   +4 more
wiley   +1 more source

Kinetic and structural characterisation of domain‐specific angiotensin I‐converting enzyme inhibition by captopril, rentiapril and zofenoprilat

The FEBS Journal, EarlyView.
Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory, Vinasha Ramasamy, Edward D. Sturrock, K. Ravi Acharya   +3 more
wiley   +1 more source

The Impact of Periodontal Health Interventions on the Risk of Ischemic Stroke: A Systematic Review and Meta‐Analysis

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim To systematically review the evidence on the relationship between periodontal health interventions and the risk of first‐ever ischemic stroke. Materials and Methods Search strategy included electronic and hand searching to January 2025. MEDLINE (OVID), EMBASE (OVID), SCOPUS, LILACS, Web of Science (WOS) and Cochrane Central Register of ...
Jorge Moldes, Joao Botelho, Manuel Rodríguez‐Yáñez, Vanessa Machado, Juan Blanco, Tomás Sobrino, Rogelio Leira, Yago Leira   +7 more
wiley   +1 more source

Effect of Post-Acute Kidney Injury Use of Renin-Angiotensin Inhibitors on Long-term Mortality and Major Adverse Kidney Events: A 5-year Retrospective Observational Cohort Study

Kidney Medicine
Rationale & Objective: Acute kidney injury (AKI) is common in hospitalized adults and a risk factor for chronic kidney disease and mortality. The effect of angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) post ...
Byorn W.L. Tan, Bryce W.Q. Tan, K. Akalya, Wei-Zhen Hong, Yi Da, Sanmay Low, Wan-Ying Ng, Horng-Ruey Chua   +7 more
doaj   +1 more source

The Optimal Dosage of Isometric Handgrip Exercise for Blood Pressure Reduction: Systematic Review and Meta-Analysis. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT The systematic review and meta‐analysis aimed to examine the dose‐response relationship between isometric handgrip (IHG) training and blood pressure outcomes in normotensive and hypertensive populations. Three databases (EMBASE, MEDLINE/PubMed, and Cochrane CENTRAL) were searched from inception to June 2025.
Lin CW, Jun IB, Igbo V, Babaniamansour A, Meng L, Lin CF, Jan YK.   +6 more
europepmc   +2 more sources

Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach

Internal Medicine Journal, EarlyView.
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich, W. P. Abhayaratna, R. Audehm, E. I. Ekinci, R. J. MacIsaac, A. J. Nelson, A. Sharma, C. Pollock   +7 more
wiley   +1 more source

Glycemic control and renal function decline in patients with chronic coronary syndrome: A multicenter cohort study

Journal of Diabetes Investigation, EarlyView.
Achieving HbA1c of 6.5–6.9% is associated with a reduced risk of renal complications in patients with diabetes and chronic coronary syndrome. Abstract Aims/Introduction Diabetes mellitus significantly contributes to renal complications, especially in patients with coronary artery disease (CAD).
An‐Yu Cheng, Chin‐Chou Huang, Hsin‐Bang Leu, Wei‐Hsian Yin, Wei‐Kung Tseng, Yen‐Wen Wu, Tsung‐Hsien Lin, Hung‐I Yeh, Kuan‐Cheng Chang, Ji‐Hung Wang, Chau‐Chung Wu, Jaw‐Wen Chen   +11 more
wiley   +1 more source

Potassium binders and continuation of renin–angiotensin system inhibitors/mineralocorticoid receptor antagonist in chronic kidney disease and heart failure (the DEMONSTRATE database)

Journal of Internal Medicine, EarlyView.
Abstract Introduction Hyperkalaemia is a serious complication in patients with chronic kidney disease (CKD) and heart failure (HF), often leading to the discontinuation of renin–angiotensin–aldosterone system inhibitors (RAASi; renin‐angiotensin system inhibitors [RASi] and mineralocorticoid receptor antagonists [MRAs]) despite their cardiorenal ...
Hans Furuland, Anders Olof Larsson, Milica Uhde, Kristel Parv, Matilda Almstedt, Thomas Cars, Maria K. Svensson   +6 more
wiley   +1 more source

Priorities for the Italian Cultural Firms [PDF]

Strategy and management are becoming priorities for the survival and growth of Italian Cultural Firms. After a decade of advantageous legislation – from several acts regarding cultural foundations to fiscal acts concerning tax incentives for private ...
Besana, Angela
core   +1 more source

Research Progress on Risk Factors for Acute Kidney Injury After Antibiotic‐Loaded Bone Cement Spacer Treatment for Periprosthetic Joint Infection

Orthopaedic Surgery, EarlyView.
During the two‐stage revision treatment of PJI patients, the use of ALCS may lead to the development of AKI, which could result in severe adverse outcomes. Despite the wide variation in the incidence of developing AKI reported in the literature, clinicians still need adequate attention, especially when confronting PJI patients who are elderly, obese ...
Lijun Cai, Xingxiao Pu, Yajie Chen, Guangtao Han, Qianhao Li, Qiuru Wang, Pengde Kang   +6 more
wiley   +1 more source