Results 71 to 80 of about 12,533 (219)
Clinical progress note: Pertussis
Visual Abstract Abstract Pertussis, commonly known as whooping cough, is a vaccine‐preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of ...
Samantha Hanna, Nicole Samies
wiley +1 more source
Differential and Temporal Immunomodulation of alpha4 Integrins on CD4+ Memory Cells by Bordetella pertussis and Bordetella parapertussis [PDF]
Pertussis, caused by Bordetella pertussis (B. pertussis), is reemerging worldwide due to vaccine inefficacy. The hallmarks of infection are extreme lymphocytosis and delayed recovery, which are partially associated with pertussis toxin.
Ravindra, Dipti
core +1 more source
[Acellular pertussis vaccine].
Protective, immunogenic, toxic, and sensitizing properties of acellular pertussis vaccine (aPV) developed according to original technology were studied, aPV had marked protective activity which lasted more than 2 years. Sera of mice immunized by aPV also possess protective properties, and they were more prominent than in sera of mice immunized by ...
N S, Zakharova +7 more
openaire +1 more source
Harnessing the Potential of mRNA Vaccines Against Infectious Diseases
RNA vaccines are promising because of their flexible design, strong immunogenicity, safety and rapid development. Recent advances have enabled mRNA vaccines to target various pathogens, including viruses such as influenza and HIV, bacteria such as Mycobacteria and Pseudomonas aeruginosa, and parasites such as those causing malaria.
Nouran Rezk, Siobhán McClean
wiley +1 more source
Management of acute bronchitis in healthy adults. [PDF]
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core
The authors demonstrate that current aP vaccines induce IL‐10‐secreting CD4+ and CD8+ Treg cells that suppress IL‐17‐secreting respiratory tissue‐resident memory (TRM) cells, and thereby fail to prevent nasal infection with B. pertussis. Blocking IL‐10R in vivo or adding a novel adjuvant LP‐GMP and intranasal delivery reverses suppression and enhances ...
Caitlín Ní Chasaide +11 more
wiley +1 more source
ABSTRACT Background Understanding the contribution of pathogens to respiratory illness in infants is important to guide interventions. We assessed the aetiology of respiratory pathogens among infants hospitalised with respiratory and non‐respiratory illness. Methods We conducted an unmatched case–control study among infants aged < 1 year.
Nicole Wolter +14 more
wiley +1 more source
Experience and challenges on influenza and pertussis vaccination in pregnant women
Young infants contribute to relatively high burden of vaccine-preventable diseases, including infections by influenza virus and Bordetella pertussis. Vaccination of pregnant women can enhance transplacental transfer of protective antibody to the fetus ...
Shabir A. Madhi, Marta C. Nunes
doaj +1 more source
Post vaccinal temporary sensorineural hearing loss [PDF]
In our systematic research we identified four studies concerning the onset of neurological adverse events following vaccination and two excluding this association.
De Cesare, Donato Pompeo +8 more
core +1 more source
ABSTRACT Background Treatment for pediatric malignancies has distinct effects on the immune system. Aims Our aim was to measure humoral immunity to measles, mumps and rubella (MMR), and diphtheria, tetanus and acellular pertussis (DTaP) vaccines after pediatric cancer treatment.
Susanna Sundell +6 more
wiley +1 more source

