Results 91 to 100 of about 12,554 (221)

Less reactogenic whole-cell pertussis vaccine confers protection from Bordetella pertussis infection

mSphere
Pertussis resurged over the last decade in most countries that replaced the traditional whole-cell pertussis vaccines (wP) by the less reactogenic acellular pertussis vaccines (aP).
Karolína Škopová, Jana Holubová, Barbora Bočková, Eva Slivenecká, João Melo Santos de Barros, Ondřej Staněk, Peter Šebo   +6 more
doaj   +1 more source

Assessment of safety and efficacy against Bordetella pertussis of a new tetanus-reduced dose diphtheria-acellular pertussis vaccine in a murine model

BMC Infectious Diseases, 2017
Background Tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccination during adolescence was introduced in response to the resurgence of pertussis in various countries.
Hyo Jin Kwon, Seung Beom Han, Bo Ram Kim, Kyu Ri Kang, Dong Ho Huh, Gi Sub Choi, Dong Ho Ahn, Jin Han Kang   +7 more
doaj   +1 more source

An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid, tetanus toxoid, 3-component acellular pertussis, hepatitis B, inactivated poliovirus, and Haemophilus influenzae type b vaccine [PDF]

, 2013
BACKGROUND: In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines.
Baker, Sherryl, Gruber, William C., Jürgens, Christine, Rose, Markus A., Schmoele-Thoma, Beate, Zielen, Stefan   +5 more
core   +1 more source

Effect of FHA and Prn on Bordetella pertussis colonization of mice is dependent on vaccine type and anatomical site.

PLoS ONE, 2020
Bordetella pertussis vaccine escape mutants that lack expression of the pertussis antigen pertactin (Prn) have emerged in vaccinated populations in the last 10-20 years.
Anne Zeddeman, Evi van Schuppen, Kristianne E Kok, Marjolein van Gent, Kees J Heuvelman, Marieke J Bart, Han G J van der Heide, Joshua Gillard, Elles Simonetti, Marc J Eleveld, Fred J H van Opzeeland, Saskia van Selm, Ronald de Groot, Marien I de Jonge, Frits R Mooi, Dimitri A Diavatopoulos   +15 more
doaj   +1 more source

Pertussis Immunization for Adolescents: What Are We Waiting for?

Canadian Journal of Infectious Diseases, 2001
Immunization against pertussis (whooping cough) has been part of the routine childhood immunization program for over 50 years. Until 1997, a whole cell pertussis vaccine was used, most often combined with diphtheria and tetanus toxoids; in some ...
SA Halperin
doaj   +1 more source

The Role of the Aceullular Pertussis Vaccine and the Comeback of 'Pertussis Pete'?

Canadian Journal of Infectious Diseases, 2001
Pertussis or whooping cough is an acute infectious disease of the respiratory tract caused principally by Bordetella pertussis and less commonly by Bordetella parapertussis (1).
John M Conly, B Lynn Johnston
doaj   +1 more source

Pediatrics [PDF]

BACKGROUNDAcellular pertussis vaccines replaced whole-cell vaccines for the 5-dose childhood vaccination series in 1997. A sixth dose of pertussis-containing vaccine, tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis, adsorbed (Tdap ...

core  

Serologic Response and Antibody-Titer Decay in Adults with Pertussis [PDF]

, 2017
Pertussis is a frequent and significant illness in adults. Because acellular pertussis vaccines for use in adolescents and adults have now been developed, it is important to compare serologic responses in adults after infection with serologic responses ...
Cherry, James D., Heininger, Ulrich, Stehr, Klemens   +2 more
core  

Pertussis Toxin: A Key Component in Pertussis Vaccines?

Toxins, 2019
B. pertussis is a human-specific pathogen and the causative agent of whooping cough. The ongoing resurgence in pertussis incidence in high income countries is likely due to faster waning of immunity and increased asymptomatic colonization in individuals ...
Kelsey A. Gregg, Tod J. Merkel
doaj   +1 more source

Evaluation of acellular pertussis vaccine: comparisons among different strains of mice. [PDF]

Emerg Microbes Infect, 2023
Wei J, Guang J, Wei C, Wang H, Zhou J, Li H, Wang L, Ma X, Yue B.   +8 more
europepmc   +1 more source