Acellular Pertussis Vaccine Components: Today and Tomorrow
Vaccines, 2020 Pertussis is a highly communicable acute respiratory infection caused by Bordetella pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks occur cyclically worldwide and effective vaccination strategies are needed
Kalyan K Dewan +2 more
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Revisiting Whooping Cough: Global Drivers and Implications of Pertussis Resurgence in the Acellular Vaccine Era [PDF]
VaccinesBackground: Whooping cough caused by Bordetella pertussis is re-emerging despite high vaccination coverage, with rising incidence in adolescents and adults in the acellular vaccine (aP) era.
Siheng Zhang, Yan Xu, Ying Xiao
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Comparing the pertussis antibody levels of healthy children immunized with four doses of DTap-IPV/Hib (Pentaxim) combination vaccine and DTaP vaccine in Quzhou, China [PDF]
Frontiers in Immunology, 2023 Despite the high coverage of pertussis vaccines in high-income countries, pertussis resurgence has been reported in recent years, and has stimulated interest in the effects of vaccines and vaccination strategies. Immunoglobulin G (IgG) antibodies against
Zhiying Yin +8 more
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Preclinical study on an adsorbed acellular diphtheria- tetanus-pertussis (reduced-dose) combined vaccine: evaluation of reproductive safety and immunogenicity [PDF]
Frontiers in ImmunologyIntroductionThe diphtheria, tetanus, and acellular pertussis combined vaccine (DTaP) is a trivalent formulation containing acellular pertussis antigens, diphtheria toxoid, and tetanus toxoid, and provides simultaneous protection against pertussis ...
Han Chu +62 more
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Bordetella pertussis Infection: From Immune Pathogenesis to Next-Generation Vaccines [PDF]
VaccinesPertussis is a highly contagious respiratory infection caused by Bordetella pertussis and remains a persistent global health challenge despite widespread vaccination. This review aims to analyze the immune pathogenesis of B.
Vasiliki E. Georgakopoulou +1 more
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Exploring the cause of the pertussis resurgence in England following the COVID-19 pandemic: a mathematical modelling study [PDF]
BMC Infectious DiseasesBackground In 2024 England, in common with many other countries, experienced a pertussis resurgence the cause of which is unclear. We used a pertussis transmission model, previously developed to investigate the cause of the pertussis resurgence in ...
Yoon Hong Choi +2 more
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Immunological Distinctions between Acellular and Whole-Cell Pertussis Immunizations of Baboons Persist for at Least One Year after Acellular Vaccine Boosting [PDF]
Vaccines, 2020 Jinrong Zhang +2 more
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Биопрепараты: Профилактика, диагностика, лечение, 2021 Some scientific publications contain data suggesting the “return” or “resurgence” of pertussis. Prevention and elimination of pertussis can only be achieved by extensive immunisation of susceptible populations with a highly effective vaccine.
I. A. Alekseeva +2 more
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Vaccines, 2022 Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Over the past years, the incidence and mortality of pertussis increased significantly. A possible cause is the switch from whole-cell to acellular pertussis vaccines,
Annieck M. Diks +12 more
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Expert Review of Vaccines, 2022 Introduction Despite high vaccination coverage among children and adolescents, pertussis remains a public health problem, with large outbreaks occurring periodically in the US and other developed countries.Areas covered We examine lessons learned more ...
Ousseny Zerbo +2 more
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