Results 11 to 20 of about 9,874 (219)

Long-term clinical course and prognosis of vaccine-related persistent itching nodules (1997–2019): An observational study

open access: yesVaccine: X, 2022
Background: Vaccines adsorbed to aluminium can induce long-lasting intensely itching subcutaneous nodules (granulomas) at the injection site as well as contact allergy to aluminium. In clinical trials of a new acellular pertussis vaccine performed in the
Anette Gente Lidholm   +4 more
doaj   +2 more sources

REACTOGENICITY OF ACELLULAR PERTUSSIS VACCINE AND THE POSSIBILITY OF ITS USE IN ELDER CHILDREN

open access: yesПедиатрическая фармакология, 2008
As is know, in the past few years, the incidence of pertussis has increased again. The article reveals the reasons of this phenomenon and the possible solutions for this problem.
M.G. Galitskaya   +4 more
doaj   +4 more sources

An infant who suffered seizures many times after pentavalent vaccination: A case report

open access: yesİstanbul Kuzey Klinikleri, 2020
Although rare, serious adverse effects may be seen after vaccination. Especially, the whole-cell pertussis vaccine has been held responsible for neurological side effects, as the most important problem in vaccination.
Meryem Erat Nergiz   +4 more
doaj   +1 more source

Pertactin-Deficient Bordetella pertussis, Vaccine-Driven Evolution, and Reemergence of Pertussis

open access: yesEmerging Infectious Diseases, 2021
Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular vaccine antigen, have raised the specter of vaccine-driven evolution and ...
Longhuan Ma   +3 more
doaj   +1 more source

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination

open access: yesScientific Reports, 2022
Infection is the most common cause of mortality early in life, yet the broad potential of immunization is not fully realized in this vulnerable population. Most vaccines are administered during infancy and childhood, but in some cases the full benefit of
David J. Dowling   +16 more
doaj   +1 more source

Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom

open access: yesEBioMedicine, 2021
Background: Pertussis can lead to serious disease and even death in infants. Older adults are more vulnerable to complications as well. In high-income countries, acellular pertussis vaccines are used for priming vaccination.
Pauline Versteegen   +15 more
doaj   +1 more source

Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

open access: yesFrontiers in Microbiology, 2020
Despite high vaccination coverage, Bordetella pertussis the causative agent of whooping cough is still a health concern worldwide. A resurgence of pertussis cases has been reported, particularly in countries using acellular vaccines with waning immunity ...
Elodie Lesne   +8 more
doaj   +1 more source

Seroprevalence of antibodies against diphtheria, tetanus, and pertussis among healthy Thai adolescents

open access: yesInternational Journal of Infectious Diseases, 2020
Objective: To determine the seroprevalence of antibodies against of diphtheria, tetanus, and pertussis among Thai adolescents. Methods: A cross-sectional study was conducted among Thai adolescents aged 11–20 years who had completed five doses of ...
Pimpika Hanvatananukul   +7 more
doaj   +1 more source

Acellular pertussis vaccine for adolescents [PDF]

open access: yesJornal de Pediatria, 2006
The use of whole-cell pertussis vaccine has led to a significant decline in incidence of the disease among children. This change in the epidemiological profile led to an increased number of cases among teenagers and adults, as a result of loss of immunity to the disease or vaccine after approximately 10 years.
Aroldo P, de Carvalho   +1 more
openaire   +2 more sources

Lack of association between mannose binding lectin and antibody responses after acellular pertussis vaccinations. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Mannose-binding lectin (MBL) is one of the key molecules in innate immunity and its role in human vaccine responses is poorly known. This study aimed to investigate the possible association of MBL polymorphisms with antibody production after ...
Kirsi Gröndahl-Yli-Hannuksela   +4 more
doaj   +1 more source

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