Results 11 to 20 of about 685,817 (173)

Parental Vaccine Hesitancy and Association With Childhood Diphtheria, Tetanus Toxoid, and Acellular Pertussis; Measles, Mumps, and Rubella; Rotavirus; and Combined 7-Series Vaccination

American Journal of Preventive Medicine, 2021
Introduction: Parental vaccine hesitancy can be a barrier to routine childhood immunization and contribute to greater risk for vaccine-preventable diseases.
Kimberly H. Nguyen, A. Srivastav, M. Lindley, Allison Fisher, David Kim, S. Greby, James Lee, J. Singleton   +7 more
semanticscholar   +1 more source

Safety and Immunogenicity of a Respiratory Syncytial Virus Prefusion F Vaccine When Coadministered With a Tetanus, Diphtheria, and Acellular Pertussis Vaccine

Journal of Infectious Diseases, 2021
Background Prevention of respiratory syncytial virus (RSV) disease in infants is an unmet vaccine need, and maternal immunization is a potential strategy to address this need.
James T. Peterson, A. Zaręba, D. Fitz-Patrick, B. Essink, D. Scott, K. Swanson, Dhawal Chelani, D. Radley, David Cooper, K. Jansen, P. Dormitzer, W. Gruber, A. Gurtman   +12 more
semanticscholar   +1 more source

Pertussis vaccines and the role of Bordetella pertussis lipooligosaccharide in the immune response to pertussis infection and vaccination

Биопрепараты: Профилактика, диагностика, лечение, 2021
Some scientific publications contain data suggesting the “return” or “resurgence” of pertussis. Prevention and elimination of pertussis can only be achieved by extensive immunisation of susceptible populations with a highly effective vaccine.
I. A. Alekseeva, O. V. Perelygina, E. D. Kolyshkina   +2 more
doaj   +1 more source

Age and Primary Vaccination Background Influence the Plasma Cell Response to Pertussis Booster Vaccination

Vaccines, 2022
Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Over the past years, the incidence and mortality of pertussis increased significantly. A possible cause is the switch from whole-cell to acellular pertussis vaccines,
Annieck M. Diks, Pauline Versteegen, Cristina Teodosio, Rick J. Groenland, Bas de Mooij, Anne-Marie Buisman, Alba Torres-Valle, Martín Pérez-Andrés, Alberto Orfao, Guy A. M. Berbers, Jacques J. M. van Dongen, Magdalena A. Berkowska, on behalf of the IMI-2 PERISCOPE Consortium   +12 more
doaj   +1 more source

An infant who suffered seizures many times after pentavalent vaccination: A case report

İstanbul Kuzey Klinikleri, 2020
Although rare, serious adverse effects may be seen after vaccination. Especially, the whole-cell pertussis vaccine has been held responsible for neurological side effects, as the most important problem in vaccination.
Meryem Erat Nergiz, Hande Yetişgin, Alperen Aydın, Gulsum Iclal Bayhan, Aysegul Nese Citak Kurt   +4 more
doaj   +1 more source

Pertactin-Deficient Bordetella pertussis, Vaccine-Driven Evolution, and Reemergence of Pertussis

Emerging Infectious Diseases, 2021
Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular vaccine antigen, have raised the specter of vaccine-driven evolution and ...
Longhuan Ma, Amanda Caulfield, Kalyan K. Dewan, Eric T. Harvill   +3 more
doaj   +1 more source

Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice

Vaccines, 2020
Bordetella pertussis whole-cell vaccines (wP) caused a spectacular drop of global pertussis incidence, but since the replacement of wP with acellular pertussis vaccines (aP), pertussis has resurged in developed countries within 7 to 12 years of the ...
J. Holubová, Ondřej Staněk, Ludmila Brázdilová, J. Masin, L. Bumba, A. Gorringe, Frances Alexander, P. Šebo   +7 more
semanticscholar   +1 more source

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination

Scientific Reports, 2022
Infection is the most common cause of mortality early in life, yet the broad potential of immunization is not fully realized in this vulnerable population. Most vaccines are administered during infancy and childhood, but in some cases the full benefit of
David J. Dowling, Soumik Barman, Alyson J. Smith, Francesco Borriello, Danielle Chaney, Spencer E. Brightman, Gandolina Melhem, Byron Brook, Manisha Menon, Dheeraj Soni, Simone Schüller, Karthik Siram, Etsuro Nanishi, Hélène G. Bazin, David J. Burkhart, Ofer Levy, Jay T. Evans   +16 more
doaj   +1 more source

Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom

EBioMedicine, 2021
Background: Pertussis can lead to serious disease and even death in infants. Older adults are more vulnerable to complications as well. In high-income countries, acellular pertussis vaccines are used for priming vaccination.
Pauline Versteegen, Marta Valente Pinto, Alex M. Barkoff, Pieter G.M. van Gageldonk, dr. Jan van de Kassteele, dr. Marlies A. van Houten, prof. Elisabeth A.M. Sanders, prof. Ronald de Groot, dr. Dimitri A. Diavatopoulos, dr. Sagida Bibi, dr. Raakel Luoto, prof. Qiushui He, dr. Anne-Marie Buisman, dr. Dominic F. Kelly, prof. Jussi Mertsola, dr. Guy A.M. Berbers   +15 more
doaj   +1 more source

Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

Frontiers in Microbiology, 2020
Despite high vaccination coverage, Bordetella pertussis the causative agent of whooping cough is still a health concern worldwide. A resurgence of pertussis cases has been reported, particularly in countries using acellular vaccines with waning immunity ...
Elodie Lesne, Breeze E. Cavell, Irene Freire-Martin, Ruby Persaud, Frances Alexander, Stephen Taylor, Mary Matheson, Cécile A. C. M. van Els, Andrew Gorringe   +8 more
doaj   +1 more source