Results 161 to 170 of about 9,874 (219)

ACELLULAR PERTUSSIS VACCINES

Pediatric Clinics of North America, 2000
Although whole-cell pertussis vaccines have been highly effective in preventing whooping cough, their common and burdensome adverse reactions have spurred the development of safer alternatives. Seven acellular vaccines are licensed in one or more countries; four have been licensed thus far in the United States, and more may follow.
M D, Decker, K M, Edwards
openaire   +4 more sources

ACELLULAR PERTUSSIS VACCINES IN ADULTS

Infectious Disease Clinics of North America, 1999
The pathogenesis of pertussis, and the epidemiology and clinical manifestations of pertussis after childhood are reviewed as a background for a discussion of recent clinical trials of acellular pertussis vaccines in adults, and the vaccines' potential for routine use in adolescents and adults.
W A, Keitel, K M, Edwards
openaire   +2 more sources

Acellular pertussis vaccines in China

Vaccine, 2012
In China, whole-cell pertussis (Pw) vaccines were produced in the early 1960s and acellular pertussis (Pa) vaccines were introduced in 1995. Pa vaccines have now almost completely replaced Pw vaccines in the national immunization program. To strengthen the regulation of vaccines used in China, a vaccine lot release system was established in 2001 and Pa
Lichan, Wang   +2 more
openaire   +2 more sources

Acellular Pertussis Vaccines for Infants

New England Journal of Medicine, 1996
Whole-cell vaccines, which are suspensions of killed Bordetella pertussis organisms, are among our most effective and least satisfactory vaccines.
K M, Edwards, M D, Decker
openaire   +2 more sources

Development of Acellular Pertussis Vaccines

Biologicals, 1999
In 1974, the authors reported the isolation and characterization of protective antigens of Bordetella pertussis in mice. With this information, an acellular pertussis vaccine was developed, composed mainly of pertussis toxin (PT) and filamentous haemagglutinin (FHA).
Y, Sato, H, Sato
openaire   +2 more sources

Acellular Pertussis Vaccine Booster

Pediatrics, 1993
The editors of Pediatrics have asked us to comment on the study by Pichichero et al,1 because our report of booster vaccination with this vaccine, published in Pediatrics in 1989,2 raised some questions with regard to the safety of the vaccine. The present study, with a design similar to ours, showed different and far more encouraging results: no ...
M, Blennow, M, Granstrom
openaire   +2 more sources

The Efficacy of Acellular Pertussis Vaccine

JAMA: The Journal of the American Medical Association, 1989
To the Editor.— Reporting from a workshop at the National Institutes of Health, Bethesda, Md, 1 Mr Marwick stated that "the large Swedish field trial of two acellular pertussis vaccines 2 has not shown levels of efficacy high enough to make either vaccine a likely candidatefor immediate licensure in the United States." We can now report efficacy data ...
P, Olin, J, Storsaeter, V, Romanus
openaire   +2 more sources

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