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Correction: Financing the introduction of new vaccines to the national immunisation programme in China: challenges and options for action. [PDF]
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Pediatric Clinics of North America, 2000
Although whole-cell pertussis vaccines have been highly effective in preventing whooping cough, their common and burdensome adverse reactions have spurred the development of safer alternatives. Seven acellular vaccines are licensed in one or more countries; four have been licensed thus far in the United States, and more may follow.
M D, Decker, K M, Edwards
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Although whole-cell pertussis vaccines have been highly effective in preventing whooping cough, their common and burdensome adverse reactions have spurred the development of safer alternatives. Seven acellular vaccines are licensed in one or more countries; four have been licensed thus far in the United States, and more may follow.
M D, Decker, K M, Edwards
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ACELLULAR PERTUSSIS VACCINES IN ADULTS
Infectious Disease Clinics of North America, 1999The pathogenesis of pertussis, and the epidemiology and clinical manifestations of pertussis after childhood are reviewed as a background for a discussion of recent clinical trials of acellular pertussis vaccines in adults, and the vaccines' potential for routine use in adolescents and adults.
W A, Keitel, K M, Edwards
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Acellular pertussis vaccines in China
Vaccine, 2012In China, whole-cell pertussis (Pw) vaccines were produced in the early 1960s and acellular pertussis (Pa) vaccines were introduced in 1995. Pa vaccines have now almost completely replaced Pw vaccines in the national immunization program. To strengthen the regulation of vaccines used in China, a vaccine lot release system was established in 2001 and Pa
Lichan, Wang +2 more
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Acellular Pertussis Vaccines for Infants
New England Journal of Medicine, 1996Whole-cell vaccines, which are suspensions of killed Bordetella pertussis organisms, are among our most effective and least satisfactory vaccines.
K M, Edwards, M D, Decker
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Development of Acellular Pertussis Vaccines
Biologicals, 1999In 1974, the authors reported the isolation and characterization of protective antigens of Bordetella pertussis in mice. With this information, an acellular pertussis vaccine was developed, composed mainly of pertussis toxin (PT) and filamentous haemagglutinin (FHA).
Y, Sato, H, Sato
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Acellular Pertussis Vaccine Booster
Pediatrics, 1993The editors of Pediatrics have asked us to comment on the study by Pichichero et al,1 because our report of booster vaccination with this vaccine, published in Pediatrics in 1989,2 raised some questions with regard to the safety of the vaccine. The present study, with a design similar to ours, showed different and far more encouraging results: no ...
M, Blennow, M, Granstrom
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The Efficacy of Acellular Pertussis Vaccine
JAMA: The Journal of the American Medical Association, 1989To the Editor.— Reporting from a workshop at the National Institutes of Health, Bethesda, Md, 1 Mr Marwick stated that "the large Swedish field trial of two acellular pertussis vaccines 2 has not shown levels of efficacy high enough to make either vaccine a likely candidatefor immediate licensure in the United States." We can now report efficacy data ...
P, Olin, J, Storsaeter, V, Romanus
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