Results 71 to 80 of about 685,817 (173)

Understanding the Epidemiology of Pertussis in Denmark

Acta Paediatrica, EarlyView.
Tine Dalby, Aoife Ronayne, Peter Henrik Andersen   +2 more
wiley   +1 more source

The Baboon as a Model to Study Human Health and Complex Disease

American Journal of Primatology, Volume 88, Issue 9, September 2026.
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley   +1 more source

The relationship between mucosal immunity, nasopharyngeal carriage, asymptomatic transmission and the resurgence of Bordetella pertussis [version 1; referees: 2 approved]

F1000Research, 2017
The incidence of whooping cough in the US has been rising slowly since the 1970s, but the pace of this has accelerated sharply since acellular pertussis vaccines replaced the earlier whole cell vaccines in the late 1990s. A similar trend occurred in many
Christopher Gill, Pejman Rohani, Donald M Thea   +2 more
doaj   +1 more source

Advances and challenges in immunotherapy for intrahepatic cholangiocarcinoma based on the tumour immune microenvironment

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
This review integrates ICC‐specific and broader BTC evidence to define how desmoplastic stroma, immune‐cell crosstalk, metabolic remodelling, and molecular heterogeneity shape immunotherapy response and resistance. It highlights biomarker‐guided, mechanism‐based combinations while emphasizing the limited maturity of ICC‐specific evidence for emerging ...
Mengyao Chen, Shuofan Jin, Yuxuan Zhou, Jinkai Tong, Yufan Zhao, Quanjun Yang   +5 more
wiley   +1 more source

Loss of Neutrophils and SLPI Reshapes Early Mucosal Inflammatory Responses During Intranasal Vaccination

European Journal of Immunology, Volume 56, Issue 9, September 2026.
Intranasal vaccination induces pulmonary neutrophil accumulation and SLPI release, accompanied by changes in soluble mediators associated with tissue remodelling, coagulation, and total IgA. ABSTRACT Vaccines delivered via the nasal route have attracted increasing attention for their capacity to engage the mucosal immune system at the primary site of ...
Oktawia Osiecka, Mariia Tyshchenko, Ivan Sinkevich, Natalia Pocałuń, Joanna Cichy, Jakub M. Kwiecinski, Ewa Oleszycka, Mieszko M. Wilk   +7 more
wiley   +1 more source

Understanding the High Incidence of Pertussis in Norway: The Role of Test Activity

Acta Paediatrica, EarlyView.
Margrethe Greve‐Isdahl, Elina Seppälä   +1 more
wiley   +1 more source

PROFILES OF CYTOKINES IN MICE DURING IMMUNIZATION WITH ADTP-VACCINE WITH ACELLULAR PERTUSSIS COMPONENT

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study cytokine status in mice immunized with vaccines containing acellular pertussis component. Materials and methods. Vaccines developed in Mechnikov RIVS - acellular pertussis vaccine (aPV) and adsorbed pertussis-diphtheria-tetanus vaccine (aDTaP),
E. M. Zaitsev, A. V. Poddubikov, M. V. Britsina, M. N. Ozeretskovskaya, N. U. Mertsalova, I. G. Bazhanova   +5 more
doaj   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Analysis of Bordetella pertussis pertactin and pertussis toxin types from Queensland, Australia, 1999–2003

BMC Infectious Diseases, 2006
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj   +1 more source

Immunogenicity and protective efficacy of a newly developed tri-component diphtheria, tetanus, and acellular pertussis vaccine in a murine model

Journal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Although assessing the immunogenicity and protective efficacy of acellular pertussis (aP) vaccines via murine model studies faces limitations, preliminary assessments have been achieved by evaluating respiratory challenge and humoral ...
Dong Ho Huh, Seung Beom Han, Hye Jo Shin, Dong Ho Ahn, Gi Sub Choi, Kyu Ri Kang, Bo Ram Kim, Jin Han Kang   +7 more
doaj   +1 more source