Results 151 to 160 of about 5,076 (258)

Upcycling Agricultural By‐Products: RNA‐Seq‐Based Elucidation of Body Weight‐Independent Hepatoprotective Mechanisms of Cucumis melo var. makuwa Leaf Extract in Diet‐Induced Obese Mice

eFood, Volume 7, Issue 3, June 2026.
Upcycling agricultural by‐products into functional resources, this study demonstrates that Cucumis melo var. makuwa leaf (CML) extract exerts a marked weight‐independent improvement of hepatic steatosis. CML extract markedly alleviates lipid accumulation, oxidative stress, and inflammation in MASLD, highlighting its potent hepatoprotective and ...
Ji Young Hwang, Ji Yun Van, Hyeon Hak Jeong, Yerin Seong, Seokmin Lee, Jaeseong Seo, Bo‐Mi Ryu, Seungjun Lee, Suhyeon Baek, Sanggil Lee, Won‐Kyo Jung, Jae‐Il Kim, Bonggi Lee   +12 more
wiley   +1 more source

Novel benzothiazole-indole acetamides as potential anticancer agents: synthesis, biological evaluation, and <i>in silico</i> studies. [PDF]

RSC Adv
Motamedi Shakib N, Negahdaripour M, Sayahi MH, Dastyafteh N, Dehghani Z, Emami M, Safapoor S, Ghasemi Y, Ghafouri SN, Ghahramani A, Mohajeri-Tehrani MR, Larijani B, Mahdavi M, Ranjbar S.   +13 more
europepmc   +1 more source

Flame‐Retardant Cellulose‐Chitosan Blend Fibers Based on Phytic Acid‐Derived Phosphorylated Ureido‐Chitosan

Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
Flame‐retardant blend fibers from cellulose and phosphorylated ureido‐chitosan are prepared via dry‐jet wet spinning from the ionic liquid 1‐ethyl‐3‐methylimidazolium octanoate and possess a limiting oxygen index (LOI) of 26.0%. ABSTRACT The synthesis of a biobased flame‐retardant additive for cellulose prepared from phytic acid‐derivatized chitosan ...
Nicolaj Wendland, Frank Hermanutz, Antje Ota, Carlo Pani, Michael R. Buchmeiser   +4 more
wiley   +1 more source

Identification of α-Azacyclic Acetamide-Based Inhibitors of <i>P. falciparum</i> Na⁺ Pump (<i>Pf</i>ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening. [PDF]

ACS Infect Dis
Casas A, Imlay LS, Thathy V, Fairhurst KJ, Lehane AM, Lawong AK, Deni I, Striepen J, Lee S, Kumar A, Xing C, Niederstrasser H, Posner BA, Laleu B, Charman SA, Fidock DA, Ready JM, Phillips MA.   +17 more
europepmc   +1 more source

Immune escape mechanisms revealed by multifunctional nanoprobes targeting PD‐L1 in hepatic cancer progression

VIEW, Volume 7, Issue 3, June 2026.
The ICGB@Apt nanoprobes are designed to specifically recognize immune checkpoint molecules such as PD‐L1, thereby enabling precise monitoring of the progression from liver cirrhosis to HC. By binding to PD‐L1 on tumor cells, ICGB@Apt visualizes immune escape events and tumor metastasis while simultaneously reflecting the dynamic interaction between ...
Yiteng Meng, Liwen Jing, Yeda Chen, Shenggang Zhan, Feng Xiong, Wenbiao Chen   +5 more
wiley   +1 more source

Design, Synthesis of Novel Quinazolinone Derivatives and Evaluation of EGFR Kinase Inhibition Activity via In Vitro and In Silico Studies

Chemical Biology &Drug Design, Volume 107, Issue 6, June 2026.
Seventeen new quinazolinone derivatives were synthesized in pure form. Compound 4j showed the highest inhibitory activity against the A549 cell line and induced apoptosis via caspase‐3 activation in MCF‐7 cells. 4j inhibited EGFR enzyme twice as effectively as gefitinib.
Aybüke Züleyha Kaya, Asaf Evrim Evren, Gülşen Akalın‐Çiftçi, Leyla Yurttaş   +3 more
wiley   +1 more source

Synthesis and bioactivity of novel 2-(1,2 benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides

ARKIVOC, 2020
Peng Yu, Xi Li, Xiao Zhang, Yanhua Xu
doaj   +1 more source

Synthesis of 2-(Quinoxalin-2-yl)acetamides and Their Preliminary Cytotoxic and Antibacterial Activity. [PDF]

Chem Biodivers
Tovar-Roman CE, Hernández-Vázquez E, Rivera-Chávez JA.   +2 more
europepmc   +1 more source

Deciphering photosynthetic protein networks: a crosslinking‐MS strategy for studying functional thylakoid membranes

The Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Photosynthesis, which sustains life on Earth, depends on organized and yet adaptable protein assemblies embedded in specialized membranes known as thylakoids. Understanding how these complexes interact and reorganize within functional photosynthetic membranes is essential to reveal the molecular basis of energy conversion in cells.
Nicolas Frances, Cecile Giustini, Giovanni Finazzi, Myriam Ferro, Pascal Albanese   +4 more
wiley   +1 more source

Design, Synthesis, and Computational Studies of Novel <i>N-</i>(Substituted phenyl)-3-(5-((naphthalen-2-yloxy)methyl)-4-phenyl‑4<i>H</i>‑1,2,4-triazol-3-ylthio)acetamides as Potent Acetylcholinesterase Inhibitors. [PDF]

ACS Omega
Ayub M, Siddiqui SZ, Rehman AU, Abbasi MA, Parveen R, Ali Shah SA, Mushtaq A, Iqbal J, Khalid H, Imran S, Abbas G.   +10 more
europepmc   +1 more source