Results 31 to 40 of about 3,911 (190)

Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors

Angewandte Chemie, EarlyView.
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Zhi Xu, Prasun Mukherjee, Steven Gossert, Stephen Thomas, Vasil H. Vasilev, Eric R. Welin, Yichen Tan, Shane M. McKenna, Megan A. Emmanuel, Todd K. Hyster   +9 more
wiley   +2 more sources

N-(3,4-Dimethylphenyl)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2007
The conformation of the N-H bond in the title compound (34DMPA), C(10)H(13)NO, is syn to the 3-methyl substituent in the aromatic ring, in contrast to the anti conformation observed with respect to the 3-chloro substituent in N-(3,4-dichloro-phen-yl)acetamide (34DCPA). The asymmetric unit of the structure contains three mol-ecules.
B. Thimme Gowda, Sabine Foro, Hartmut Fuess   +2 more
openaire   +3 more sources

Synthetic approaches to multifunctional indenes

Beilstein Journal of Organic Chemistry, 2011
The synthesis of multifunctional indenes with at least two different functional groups has not yet been extensively explored. Among the plausible synthetic routes to 3,5-disubstituted indenes bearing two different functional groups, such as the [3 ...
Neus Mesquida, Sara López-Pérez, Immaculada Dinarès, Ermitas Alcalde   +3 more
doaj   +1 more source

N-(3-Bromophenyl)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
The conformation of the N-H bond in the structure of the title compound, C(8)H(8)BrNO, is anti to the C=O bond and to the meta-bromo substituent of the aromatic ring in both independent mol-ecules comprising the asymmetric unit. Mol-ecules are linked through N-H⋯O hydrogen bonding into supra-molecular chains with a twisted topology.
Hartmut Fuess, Hiromitsu Terao, Sabine Foro, B. Thimme Gowda   +3 more
openaire   +3 more sources

Direct acylation of aryl amines using dimethylformamide and dimethylacetamide as the acyl resources

Journal of Saudi Chemical Society, 2016
The treatment of aryl amines with dimethylformamide (DMF) and dimethylacetamide (DMA) in the presence of hydrochloric acid brings about efficient N-acylation to give the corresponding aryl formamides and aryl acetamides in acceptable to excellent yields.
Qing Zhang, Cui Chen
doaj   +1 more source

N-(3,4-Diethoxyphenyl)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the title compound, C12H17NO3, the conformations of the N—H and C=O bonds areantito each other. In the crystal structure, N—H...O hydrogen-bond interactions help to establish the packing.
Pei-Hua Ma, Kai-Zhi Zhou, Mei-Lian Sun, Xiu-Mei Zhao, Xin Xiao   +4 more
openaire   +3 more sources

Synthesis, structure and properties of N-R-2-(5-(5-methyl-1H-pyrazole-3-yl)-4-phenyl-4H-1,2,4-triazole-3-ylthio)acetamides

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Heterocyclic compounds remain the most promising group of compounds, through which the new drugs with characteristic list of properties are successfully created. Examples of this systems are 1,2,4-triazole and pyrazole.
A. S. Hotsulia, S. O. Fedotov
doaj   +1 more source

N-(2-Chlorophenylsulfonyl)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
The asymmetric unit of the title compound, C(8)H(8)ClNO(3)S, contains two independent mol-ecules in which the C-S-N-C torsion angles are -71.7 (3) and 61.2 (3)°. The benzene rings and the SO(2)-NH-CO-C segments form dihedral angles of 80.2 (1) and 88.1 (2)° in the two independent mol-ecules. In the crystal, inter-molecular N-H⋯O hydrogen bonds link the
K. Shakuntala, Sabine Foro, B. Thimme Gowda   +2 more
openaire   +3 more sources

Rational Design of Ni3+‐Rich Nickel Nitride Enables Paired Electrooxidation of Sterol and Hydrogen Evolution in a Flow Electrolyzer

Advanced Science, EarlyView.
The rational design of Ni3+‐rich active sites on nickel nitride nanosheets via Pd‐induced electronic modulation, which was employed in the electrooxidation of sterol coupled with H2 production in a large flow electrolyzer. This work offers a novel strategy for the design and synthesis of highly efficient electrocatalysts and electrolyzers toward the ...
Suiqin Li, Jieyu Wang, Ge Feng, Jiahui He, Kai Li, Lihao Liu, Yuhang Wang, Zixian Jia, Yanfei Xu, Wenwu Zhong, Xing Zhong, Jianguo Wang   +11 more
wiley   +1 more source

Synthesis of Tetrahydroberberine N,N-Derived O-Acetamides

Molbank
The reaction of berberine derivatives containing at the O-9 position N,N-disubstituted acetamide fragments with sodium borohydride in methanol at 0 °C leads to a mild reduction of the “C” cycle with the formation of corresponding tetrahydroberberine ...
Ivan Vasil’evich Nechepurenko, Nina Ivanovna Komarova, Nariman Faridovich Salakhutdinov   +2 more
doaj   +1 more source