Results 21 to 30 of about 7,268 (257)

Synthesis of acetamides bearing 3-aryl-3,4-dihydroquinazolin-4-one and 2-thioxothiazolidin-4-one moieties as novel derivatives

Vietnam Journal of Science, Technology and Engineering, 2022
Five new derivatives of N-(4-oxo-2-thioxothiazolidin-3-yl)-2-((3-aryl-4-oxo-3,4-dihydroquinazolin-2-yl)thio) acetamides have been synthesized successfully through a four-step process from anthranilic acid and aryl isothiocyanates as starting materials ...
Tien Cong Nguyen, Duc Dung Pham, Thi Minh Dinh Tran, Thi Thuy Linh Bui   +3 more
doaj   +1 more source

The synthesis and biological assessment of [[1,2,4]triazolo[4,3-a]pyridine-3-yl]acetamides with an 1,2,4-oxadiazol cycle in positions 6, 7 and 8

Журнал органічної та фармацевтичної хімії, 2019
Fused heterocyclic 1,2,4-triazoles have provided much attention due to variety of their interesting biological properties. Aim. To develop the method for the synthesis of novel 2-[(1,2,4-oxadiazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridine-3-yl]acetamides and
V. R. Karpina, S. S. Kovalenko, S. M. Kovalenko, O. V. Zaremba, O. V. Silin, T. Langer   +5 more
doaj   +1 more source

Toxicidade do herbicida S-metolachlor em plantas de milho provenientes de sementes com diferentes formatos e dimensões S-metholachlor toxicity in maize plants originated from seeds with different sizes and shapes

Planta Daninha, 2006
Este trabalho teve como objetivo avaliar a toxicidade do herbicida S-metolachlor em plantas de milho oriundas de sementes com diferentes características morfológicas.
M.D.A. Rosenthal, S.O. Procópio, J.J.O. Pinto, E.A. Jacob Júnior, W.B. Peres, R. Manica, J.F. Zanatta, A. Cargnelutti Filho, D.C. Sganzerla, J.C. Carneiro, L.G. Canabarro, W. Franzini   +11 more
doaj   +1 more source

Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds [PDF]

, 2018
Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use of molecular oxygen.
Domínguez Pérez, Pilar Esther, Herrero Corral, María Teresa, San Martín Faces, Raúl, Urgoitia Gabikaetxebarria, Garazi   +3 more
core   +3 more sources

Determination of protonation constants and structural correlations for some tertiary formamides and acetamides in sulfuric acid with UV spectroscopy

Macedonian Journal of Chemistry and Chemical Engineering, 2015
The protonation of ten aliphatic amides in sulfuric acid media was studied by UV spectroscopy. The pKBH+ values and solvation parameters were calculated using Yates and McClelland Method, Excess Acidity Method and Bunnett and Olsen Method.
Goran Stojković, Elizabeta Dimitrieska-Stojković, Emil Popovski   +2 more
doaj   +1 more source

Novel synthetic routes to thienocarbazoles via palladium or copper catalyzed amination or amidation of arylhalides and intramolecular cyclization [PDF]

, 2002
Palladium or copper catalyzed aminations or amidations were performed to obtain diarylamines and diarylacetamides precursors of thienocarbazoles. The fact that an ortho-bromodiarylamine didn’t cyclize to the corresponding thienocarbazole under conditions
Cagniant, Cagniant, Chakraborty, Dalton, Dougherty, Ferreira, Freeman, Gilbert Kirsch, Ihmels, Isabel C.F.R Ferreira, Iwaki, Knölker, Knölker, Maria-João R.P Queiroz, Ostrovidov, Patani, Peixoto, Pierre, Pierre, Rosseau-Richard, Thornerm, Wolfe   +21 more
core   +2 more sources

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

Angewandte Chemie, EarlyView.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach, Ioanna Tsiara, Wawrzyniec Haberek, Weifeng Lin, Daniel Globisch   +4 more
wiley   +2 more sources

Synthesis of new chiral organosulfur donors with hydrogen bonding functionality and their first charge transfer salts [PDF]

, 2013
The syntheses of a range of enantiopure organosulfur donors with hydrogen bonding groups are described including TTF related materials with two, four, six and eight hydroxyl groups and multiple stereogenic centres and a pair of chiral N-substituted BEDT ...
Akutsu, H, Awheda, I, Brooks, AC, Day, P, Guziak, MA, Horton, PN, Krivickas, SJ, Le Kerneau, M, Martin, L, Pelletier, F, Wallis, JD, Yang, S   +11 more
core   +1 more source

RaPID Selection of Backbone Macrocyclic Peptides Targeting Akt2

Angewandte Chemie, EarlyView.
Backbone macrocyclic peptide library (BMP) library was screened against Akt2 via RaPID to discover potent BMPPakti‐3 (IC50 = 34 nM). ABSTRACT Backbone‐cyclic peptides (BMPs) are an attractive class of molecules appeared in diverse natural bioactive products. However, mRNA display technology coupled with ribosomal synthesis is intrinsically inapplicable
Koki Shinbara, Ekishin Yanagi, Ayaka Aizawa, Takayuki Katoh, Hiroaki Suga   +4 more
wiley   +2 more sources

N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor. [PDF]

, 2004
We report the synthesis and the affinity data at both the peripheral (PBR) and the central benzodiazepine receptors of a series of N,N-dialkyl-2-phenylindol-3-ylglyoxylamide derivatives III, designed as conformationally constrained analogues of 2 ...
B. CHELLI, B. COSTA, C. MARTINI, E. ABIGNENTE DI FRASSELLO, E. NOVELLINO, F. DA SETTIMO, F. SIMORINI, G. GRECO, G. PRIMOFIORE, M.P. PATRIZI, S. TALIANI   +10 more
core   +1 more source