Results 31 to 40 of about 4,030 (217)
Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides
Angewandte Chemie, EarlyView.Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok +4 more
wiley +2 more sources
A High‐Voltage Membrane‐Free Li–Organic Hybrid Flow Battery Using Eutectic Lithium Chemistry
Angewandte Chemie, EarlyView.A high‐voltage (3.6 V) membrane‐free Li–organic hybrid flow battery is enabled by a deep‐eutectic lithium electrolyte composed of trifluoroacetamide (TFAD) and LiPF6, paired with a dichloromethane (DCM) catholyte containing phenothiazine (PTZ). The TFAD/LiPF6 eutectic provides fast Li+ transport and stable Li‐metal cycling, while the immiscible TFAD ...
Xiao Wang +7 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Enantioselective aminoarylation of ortho‐allyl anilines is achieved under mild conditions. Key to success is the electrostatically‐directed nature of the key aminopalladation step, achieved by using the sulfonated chiral ligand sSPhos on palladium. A detailed study of electronic trends allows tuning of the sulfonamide protecting group to enable good ...
Max Kadarauch +4 more
wiley +2 more sources
Synthetic approaches to multifunctional indenes
Beilstein Journal of Organic Chemistry, 2011 The synthesis of multifunctional indenes with at least two different functional groups has not yet been extensively explored. Among the plausible synthetic routes to 3,5-disubstituted indenes bearing two different functional groups, such as the [3 ...
Neus Mesquida +3 more
doaj +1 more source
Induction and Stabilization of Peptide Alpha‐Helices on Silica Nanoparticles
Angewandte Chemie, EarlyView.Covalent docking turns silica nanoparticles (SNPs) into α‐helix‐stabilizing surfaces. Dynamic imine formation allows peptides with lysine residues aligned on one helical face to adapt to the surface before reduction locks the structure in place, while preserving the opposite face for functional recognition.
Fidel Lozano‐Elena +3 more
wiley +2 more sources
Direct acylation of aryl amines using dimethylformamide and dimethylacetamide as the acyl resources
Journal of Saudi Chemical Society, 2016 The treatment of aryl amines with dimethylformamide (DMF) and dimethylacetamide (DMA) in the presence of hydrochloric acid brings about efficient N-acylation to give the corresponding aryl formamides and aryl acetamides in acceptable to excellent yields.
Qing Zhang, Cui Chen
doaj +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019 Heterocyclic compounds remain the most promising group of compounds, through which the new drugs with characteristic list of properties are successfully created. Examples of this systems are 1,2,4-triazole and pyrazole.
A. S. Hotsulia, S. O. Fedotov
doaj +1 more source
Advanced Science, EarlyView.A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan +5 more
wiley +1 more source
Synthesis of Tetrahydroberberine N,N-Derived O-Acetamides
MolbankThe reaction of berberine derivatives containing at the O-9 position N,N-disubstituted acetamide fragments with sodium borohydride in methanol at 0 °C leads to a mild reduction of the “C” cycle with the formation of corresponding tetrahydroberberine ...
Ivan Vasil’evich Nechepurenko +2 more
doaj +1 more source