Results 61 to 70 of about 5,076 (258)

N-(4-Isopropoxyphenyl)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the mol-ecule of the title compound, C(11)H(15)NO(2), the planar acetamide unit [maximum deviation of 0.0014 (6) Å] is oriented at a dihedral angle of 19.68 (4)° with respect to the aromatic ring. An intra-molecular C-H⋯O inter-action results in the formation of a six-membered ring. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link
Hai-Bo Wang, Wen-Bin Wei, Lu-Na Han, Ran-Zhe Lu, Min Zhang   +4 more
openaire   +3 more sources

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Bis-pyrimidine acetamides: design, synthesis and biological evaluation

Chemistry Central Journal, 2017
Background In the past few years, increased resistance of microorganisms towards antimicrobial agents become a serious health problem, so there is a need for the discovery of new antimicrobial agents.
Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Balasubramanian Narasimhan   +5 more
doaj   +1 more source

Eschenmoser coupling reactions starting from primary thioamides. When do they work and when not?

Beilstein Journal of Organic Chemistry, 2023
Reactions of thiobenzamide or thioacetamide with 4-bromo-1,1-dimethyl-1,4-dihydroisoquinoline-3(2H)-one, 4-bromoisoquinoline-1,3(2H,4H)-dione and two α-bromo(phenyl)acetamides were examined under various conditions (base, solvent, thiophile, temperature)
Lukáš Marek, Jiří Váňa, Jan Svoboda, Jiří Hanusek   +3 more
doaj   +1 more source

Synthesis of Substituted Acetamides as Potential Antibacterial and Antiviral Agents

, 1985
Department of Chemistry, Lucknow University, Lucknow-226 007 Plant Virus Laboratory, Lucknow University, Lucknow-226 007 Manuscript received 30 April 1984, accepted 18 January 1985 Synthesis of Substituted Acetamides as Potential Antibacterial and ...
ASHOK K. PANDEY, H. N. VERMA, ANIL K. SENGUPTA, M. M. A. A. KHAN   +3 more
core   +1 more source

Intramolecular Carbene C-H Insertion Reactions of 2-Diazo-2-sulfamoylacetamides

Molecules, 2019
The intramolecular C-H insertions of carbenes derived from 2-diazo-2-sulfamoylacetamides were studied. 2-Diazo-2-sulfamoylacetamides were first prepared from chloroacetyl chloride and secondary amines through acylation followed by sequential treatments ...
Chuqiang Que, Peipei Huang, Zhanhui Yang, Ning Chen, Jiaxi Xu   +4 more
doaj   +1 more source

Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity. [PDF]

, 2016
3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial activity but lacked activity ...
Kaiser, M, Wilkinson, SR, Wilkinson, Shane R., Rosenzweig, Howard S., Kaiser, Marcel, Szular, Joanna, Szular, J, Papadopoulou, Maria V., Bloomer, William D., Papadopoulou, MV, Bloomer, WD, Rosenzweig, HS   +11 more
core   +1 more source

Synthesis and Antimicrobial Activity of Some Novel Substituted Piperazinyl-quinazolin-3(4H)-ones

E-Journal of Chemistry, 2008
Several substituted-quinazolin-3(4H)-ones were synthesized by condensation of 2-chloro-N-(4-oxo-substituted-quinazolin-3(4H)-yl)-acetamides with various substituted piperazines through single step reaction. Elemental analysis, IR, 1HNMR and mass spectral
N. M. Raghavendra, P. P. Thampi, P. M. Gurubasavarajaswamy   +2 more
doaj   +1 more source

Author Correction: Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1. [PDF]

Nat Commun
Author Correction: Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein ...
Dans MG, Boulet C, Watson GM, Nguyen W, Dziekan JM, Evelyn C, Reaksudsan K, Mehra S, Razook Z, Geoghegan ND, Mlodzianoski MJ, Goodman CD, Ling DB, Jonsdottir TK, Tong J, Famodimu MT, Kristan M, Pollard H, Stewart LB, Brandner-Garrod L, Sutherland CJ, Delves MJ, McFadden GI, Barry AE, Crabb BS, de Koning-Ward TF, Rogers KL, Cowman AF, Tham WH, Sleebs BE, Gilson PR.   +30 more
europepmc   +2 more sources

2-(4-Iodophenoxy)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
The mol-ecule of the title compound, C(8)H(8)INO(2), amide-typical resonance shortens the nominal C-N single bond to 1.322 (7) Å. In the crystal, hydrogen bonds involving both nitro-gen-bound H atoms as well as C-H⋯O contacts connect the mol-ecules into double layers approximately perpendicular to the crystallographic b axis.
Richard Betz, Cedric McCleland, Stephen Glover   +2 more
openaire   +3 more sources