Results 151 to 160 of about 88,369 (298)

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

Phytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao, Alimu Tulahong, Xinlu Xu, Tiemin Jiang, Ruiqing Zhang, Yanze Lin, Zhongdian Yuan, Rexiati Ruze, Yingmei Shao   +8 more
wiley   +1 more source

Yellow Granular Material in Hair: A Bedside Clue to Overdose from Cold Medication Containing Acetaminophen. [PDF]

Clin Pract Cases Emerg Med
Sakamoto S.
europepmc   +1 more source

Electrochemistry of Acetaminophen

The contribution is focused on electrochemical oxidation of acetaminophen mainly in non-aqueous media. The influence of various organic solvents as well as the pH effect is described herein.
Mikysek, T.
core  

Oxypaeoniflorin Attenuates Alcohol‐Associated Liver Disease, Potentially Involving TEAD4‐Mediated Inflammatory Signaling Cascades

Phytotherapy Research, EarlyView.
Oxypaeoniflorin (Opae) alleviates alcohol‐associated liver disease (ALD) by suppressing the TEAD4‐NLRP3 transcriptional axis. In hepatocytes, Opae inhibits YAP/TEAD4‐mediated NLRP3 inflammasome activation, thereby downregulating Lipin1/Srebp1‐associated lipid dysregulation.
Jiang‐Tao Zhong, Hao Yue, Ze‐Hao Wang, Ming Liu, Hai‐Ming Sun, Jian Song   +5 more
wiley   +1 more source

Acetaminophen versus Ibuprofen for the management of hemodynamically significant patent ductus arteriosus in very low birth weight infants: randomized trial. [PDF]

J Pediatr (Rio J)
Bancalari A, Contreras H, Díaz V, Giaconi J, Henriquez I, Pérez G, Marinovic A.   +6 more
europepmc   +1 more source

What If Cooking Isn't Chemistry? Examining the Good and the Harm in Metaphorical Connections Between Science and Everyday Activities

Science Education, EarlyView.
ABSTRACT This theoretical paper examines why we make claims like “cooking is chemistry,” what these claims mean, and what good or harm they accomplish. We make three interrelated arguments: First, the relationship between scientific and everyday practices is more complicated and less obvious than is often claimed; second, educators and scientists link ...
Noah Weeth Feinstein, Ryan L. Stowe
wiley   +1 more source

Effects of Fomepizole on Acetaminophen Oxidative Metabolism: A Randomized, Crossover Study in Human Volunteers. [PDF]

Clin Pharmacol Ther
Anand S, Buckley NA, Stathakis P, James L, Parker L, McGill MR, Chiew AL.   +6 more
europepmc   +1 more source

AI‐enabled engineering of hesperidin/ursodeoxycholic acid nanomedicine for synergistic treatment of drug‐induced liver injury

Smart Molecules, EarlyView.
An AI‐driven framework integrating disease‐network analysis, direction‐aware molecular screening, and carrier‐free co‐assembly engineering enables nanomedicine design. The dual‐constraint deep learning model predicts API–target affinity and regulatory direction to prioritize complementary APIs.
Kai Xiao, Meng Fan, Haoyu Zheng, Boyuan Gu, Shaowen Wang, Ziping Wu, Shiming Zhang, Xin Zhao, Wensheng Zhang, Quanxin Ning, Sigen A, Chao Yang, Huayi Sun, Ren Mo, Dan Shao   +14 more
wiley   +1 more source

Acetaminophen toxicity: Patterns of liver injury, effects on hospital length of stay, and the need for inpatient psychiatric care. [PDF]

Hepatol Forum
Ozturk NB, Da BL, Ezaz G, Schiano TD.
europepmc   +1 more source

Exploratory MRI and Clinical Marker Analysis of Pustulotic Arthro‐Osteitis Disease Activity From a Phase 3 Brodalumab Trial

The Journal of Dermatology, EarlyView.
ABSTRACT Pustulotic arthro‐osteitis (PAO) is a clinically important osteoarticular comorbidity affecting approximately 9%–28% of patients with palmoplantar pustulosis (PPP), yet early recognition and standardized activity assessment remain challenging, particularly in routine dermatology practice.
Taiki Nozaki, Manabu Arai, Junko Ochi, Mona Uchida‐Yamada, Masahiro Hashimoto, Mitsuhiro Akiyama, Yuko Kaneko, Yasumasa Kanai, Masahiro Jinzaki   +8 more
wiley   +1 more source