Results 161 to 170 of about 88,369 (298)

Acetaminophen Overdose and Self-Induced Ethanol Enema. [PDF]

Cureus
Ghotra A, Mangat NK, Karki BR, Twersky Y.   +3 more
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Volumetric Absorptive Microsampling During Spaceflight for Analysis of Acetaminophen Pharmacokinetics in Whole Blood. [PDF]

J Clin Pharmacol
Mampre D, Guttendorf R, Zimmer J, Whitson B, Huggins J, Christianson C, Burns E, Heft N, Rosenberg M, Asadi A, Mateus J, Rudge J, Mizuno T, Donehoo J.   +13 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

HK1-LDHA axis feedback regulation promotes histone lactylation of Wnt5a and mediates prenatal acetaminophen-induced susceptibility to osteoarthritis in male offspring. [PDF]

Exp Mol Med
Zhang F, Li Q, Sun X, Guo Y, Wang H, Chen L.   +5 more
europepmc   +1 more source

Acetaminophen in Perspective [PDF]

Journal of the American Geriatrics Society, 2016
openaire   +2 more sources

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Prenatal over-the-counter acetaminophen use and birth outcomes in the ECHO Cohort. [PDF]

Am J Epidemiol
Huff KK, Galai N, Fuselier G, Wu G, Hartwell HJ, Bulka CM, Adgent MA, Alshawabkeh AN, Baker BH, Talavera-Barber MM, Bekelman TA, Cowell W, Duberstein ZT, Elliott AJ, Enquobahrie DA, Ghassabian A, Karagas MR, Kautz A, Lester BM, Ma T, McEvoy CT, McKee KS, Meeker JD, Nguyen RHN, O'Connor TG, Paneth N, Perng W, Porucznik CA, Sathyanarayana S, Simhan HN, Swan SH, Woodbury ML, Ehrhardt S, O'Shea TM, Fry RC, For The Echo Cohort Consortium.   +35 more
europepmc   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Uncertain timing of reported acetaminophen ingestion in an adolescent analgesic overdose: a case report. [PDF]

Front Pediatr
Alghamdi WA.
europepmc   +1 more source