Results 171 to 180 of about 88,369 (298)

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small‐Cell Lung Cancer Models

Cancer Science, EarlyView.
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Kyoji Tsurumi, Miyuki Nomura, Mai Ouchi, Shigehiro Yagishita, Naohiko Kikuchi, Taku Sato, Mami Morita, Yoji Yamashita, Kayoko Hayashi, Tomoyoshi Soga, Akinobu Hamada, Tatsuro Fukuhara, Nobuhiro Tanuma   +12 more
wiley   +1 more source

Drug-induced enterocolitis syndrome triggered by mefenamic acid in a child: TARC and DLST as diagnostic aids. [PDF]

Pediatr Allergy Immunol
Ishikura T, Masumoto N, Yoshimoto Y, Lee S.   +3 more
europepmc   +1 more source

Exploring Culturally Safe Oral Health Services for a Regional Aboriginal Community in Victoria

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives National policies have been introduced to promote the delivery of Culturally Safe dental care for Aboriginal and Torres Strait Islander Australians. However, the understanding of what constitutes Culturally Safe dental care and how it can be effectively implemented into clinical practice, remains limited.
Eliza Collins, Shawana Andrews, Julie Satur   +2 more
wiley   +1 more source

Comparison of the efficacy and safety of acetaminophen versus NSAIDs for the treatment of chronic pain in older adults with osteoarthritis of the hip and knee: Findings from the randomized, double-blind, parallel-group, non-inferiority RETHINK study. [PDF]

Osteoarthr Cartil Open
Endo M, Kawano T, Tokunaga M, Kawahara S, Mawatari T, Hara T, Tashiro Y, Matsuda M, Sato T, Baba S, Hamasaki A, Takano T, Miyake M, Aono H, Sakamoto S, Miyaji T, Shimokawa M, Zenda S, Nakashima Y, RETHINK study group.   +19 more
europepmc   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

Association of serum acetaminophen levels with hepatorenal toxicity: A prospective observational study in Tripura, India. [PDF]

Indian J Pharmacol
Ray D, Goswami B, Nath S, Saha P, Sengupta S.   +4 more
europepmc   +1 more source

Combined dorsal and ventral rhizotomy in non‐ambulatory individuals with mixed spastic bilateral cerebral palsy: A prospective registry analysis

Developmental Medicine &Child Neurology, EarlyView.
This is the largest North American study of combined dorsal/ventral rhizotomy in non‐ambulatory, bilateral, mixed spastic–dyskinetic cerebral palsy (33 patients). Combined rhizotomy was safe, improved dystonia (Barry–Albright Dystonia Scale), spasticity (modified Ashworth scale), quality of life (Caregiver Priorities and Child Health Index of Life with
Adam C. Glaser, Joon Hyeok Choi, Kristin Buxton, Nahyun Kim, Juliana Mariani, Benjamin J. Shore, Weston T. Northam   +6 more
wiley   +1 more source

Prenatal exposure to paracetamol and the risk of autism and attention‐deficit/hyperactivity disorder: An umbrella review and meta‐meta‐analysis

Developmental Medicine &Child Neurology, EarlyView.
This meta‐meta‐analysis synthesizes evidence on prenatal paracetamol exposure and neurodevelopmental outcomes. Crude analyses suggest small associations with autism and ADHD, but these attenuate substantially when restricting to high‐quality meta‐analyses and low‐bias primary studies.
Hoda Tayebi‐Hillali, María Blanco‐Suárez, Berta Rivas‐Mundiña, Jacobo Limeres‐Posse, Márcio Diniz‐Freitas, Pedro Diz‐Dios   +5 more
wiley   +1 more source

On-Demand Acetaminophen Versus Scheduled Diclofenac-Serratiopeptidase After Cesarean Delivery: A Randomized Controlled Trial. [PDF]

Cureus
Yaliwal RG, Sree DN, K AH, Kori S.
europepmc   +1 more source

The role of <i>Lactobacillus plantarum</i> (camel milk isolate) in inflammation and acute pain modulation: a comparative study with acetaminophen in animal model. [PDF]

Ann Med Surg (Lond)
Ahmadi S, Khosravipour N, Pedram-Jafari S, Dashti S, Taherkhani S, Nasiraie LR, Janzadeh A.   +6 more
europepmc   +1 more source