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Gastroenterology, 1980
This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
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This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
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Paediatric Respiratory Reviews, 2013
Acetaminophen is a widely used medication for the treatment of pain and fever in children and pregnant women. There is substantial epidemiological evidence in adults and children that acetaminophen use is associated with asthma symptoms. There is also a considerable body of evidence that supports a modest but consistent association of acetaminophen use
A John, Henderson, Seif O, Shaheen
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Acetaminophen is a widely used medication for the treatment of pain and fever in children and pregnant women. There is substantial epidemiological evidence in adults and children that acetaminophen use is associated with asthma symptoms. There is also a considerable body of evidence that supports a modest but consistent association of acetaminophen use
A John, Henderson, Seif O, Shaheen
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Clinics in Laboratory Medicine, 2006
Acetaminophen (acetyl-para-amino-phenol or APAP), an antipyretic and analgesic, is a common component in hundreds of over-the-counter and prescription medications. The wide usage of this drug results in many potentially toxic exposures. It is therefore critical for the clinician to be comfortable with the diagnosis and treatment of APAP toxicity ...
Adam K, Rowden +3 more
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Acetaminophen (acetyl-para-amino-phenol or APAP), an antipyretic and analgesic, is a common component in hundreds of over-the-counter and prescription medications. The wide usage of this drug results in many potentially toxic exposures. It is therefore critical for the clinician to be comfortable with the diagnosis and treatment of APAP toxicity ...
Adam K, Rowden +3 more
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Orthopaedic Nursing, 1997
Acetaminophen is the most widely used and recommended nonprescription analgesic and antipyretic medication in the United States (Rose, 1994). Because acetaminophen is widely advertised and readily available over the counter, consumers as well as health care professionals perceive this medication to be nontoxic.
J A, Roach, B, Stacey
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Acetaminophen is the most widely used and recommended nonprescription analgesic and antipyretic medication in the United States (Rose, 1994). Because acetaminophen is widely advertised and readily available over the counter, consumers as well as health care professionals perceive this medication to be nontoxic.
J A, Roach, B, Stacey
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The American Journal of Medicine, 1983
Acetaminophen is a remarkably safe agent when used in therapeutic doses. Most reported overdoses of acetaminophen are the result of suicide attempts. The clinical course of patients with toxic blood levels follows four distinct stages. Symptoms of nausea, vomiting, diaphoresis, and anorexia usually begin within seven to 14 hours after ingestion.
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Acetaminophen is a remarkably safe agent when used in therapeutic doses. Most reported overdoses of acetaminophen are the result of suicide attempts. The clinical course of patients with toxic blood levels follows four distinct stages. Symptoms of nausea, vomiting, diaphoresis, and anorexia usually begin within seven to 14 hours after ingestion.
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Emergency Medicine Clinics of North America, 1984
N-acetylcysteine (NAC) is the treatment of choice for acetaminophen overdose. With this therapy, morbidity from overdose can be held to a minimum. Mortality is rare in any case and virtually nonexistent in treated patients. Unless a high index of suspicion is maintained, the diagnosis may be missed until it is too late for effective antidotal treatment.
C H, Linden, B H, Rumack
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N-acetylcysteine (NAC) is the treatment of choice for acetaminophen overdose. With this therapy, morbidity from overdose can be held to a minimum. Mortality is rare in any case and virtually nonexistent in treated patients. Unless a high index of suspicion is maintained, the diagnosis may be missed until it is too late for effective antidotal treatment.
C H, Linden, B H, Rumack
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Anesthesiology Clinics, 2010
Acetaminophen has unique analgesic and antipyretic properties. It is globally recommended as a first-line agent for the treatment of fever and pain due to its few contraindications. Acetaminophen lacks the significant gastrointestinal and cardiovascular side effects associated with nonsteroidal anti-inflammatory drugs and narcotics.
Jonathan S, Jahr, Vivian K, Lee
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Acetaminophen has unique analgesic and antipyretic properties. It is globally recommended as a first-line agent for the treatment of fever and pain due to its few contraindications. Acetaminophen lacks the significant gastrointestinal and cardiovascular side effects associated with nonsteroidal anti-inflammatory drugs and narcotics.
Jonathan S, Jahr, Vivian K, Lee
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Orthopaedic Nursing, 2015
Acetaminophen is a nonsteroidal, nonsalicylate analgesic and antipyretic that is, today, the most common medication ingredient found in oral and rectal over-the-counter and prescription drugs. However, it was not until 2010 that Ofirmev (acetaminophen), an injection form of acetaminophen, was approved for treating mild to moderate pain, as an adjunct ...
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Acetaminophen is a nonsteroidal, nonsalicylate analgesic and antipyretic that is, today, the most common medication ingredient found in oral and rectal over-the-counter and prescription drugs. However, it was not until 2010 that Ofirmev (acetaminophen), an injection form of acetaminophen, was approved for treating mild to moderate pain, as an adjunct ...
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Acetaminophen for osteoarthritis
2003Osteoarthritis (OA) is the most common form of arthritis. Published guidelines and expert opinion are divided over the relative role of acetaminophen (also called paracetamol or Tylenol) and non-steroidal anti-inflammatory drugs (NSAIDs) as first-line pharmacologic therapy.
T E, Towheed +3 more
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Digestive Diseases and Sciences, 2000
To determine the influence of psychosocial factors in accidental and deliberate acetaminophen overdose, we reviewed the charts of 207 overdose patients, and 48 met our criteria for acetaminophen toxicity. Two patients died. A psychiatric history was present in 75%, and 25% had a previous or subsequent suicide attempt.
T A, Broughan, R D, Soloway
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To determine the influence of psychosocial factors in accidental and deliberate acetaminophen overdose, we reviewed the charts of 207 overdose patients, and 48 met our criteria for acetaminophen toxicity. Two patients died. A psychiatric history was present in 75%, and 25% had a previous or subsequent suicide attempt.
T A, Broughan, R D, Soloway
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