Results 81 to 90 of about 136,607 (334)
Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila
Scientific Reports, 2022 Acetaminophen is the most common cause of acute drug-induced liver injury in the United States. However, research into the mechanisms of acetaminophen toxicity and the development of novel therapeutics is hampered by the lack of robust, reproducible, and
Bejan J. Saeedi +5 more
doaj +1 more source
Attenuation of hemodynamic responses to laryngoscopy and tracheal intubation: Propacetamol versus lidocaine - A randomized clinical trial [PDF]
, 2014 The purpose of this study is to assess the effects of propacetamol on attenuating hemodynamic responses subsequent laryngoscopy and tracheal intubation compared to lidocaine.
Darabi, H. +11 more
core +4 more sources
Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features
Chemistry &Biodiversity, EarlyView.ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad +5 more
wiley +1 more source
ChemMedChem, Accepted Article.Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore +5 more
wiley +1 more source
PLoS ONE, 2015 BackgroundIt has been observed that acetaminophen potentiates the analgesic effect of morphine and tramadol in postoperative pain management. Its capacity as an analgesic drug or in combinations thereof to reduce the minimum alveolar concentration (MAC ...
Julio R Chavez +5 more
doaj +1 more source
Antidote application: an educational system for treatment of common toxin overdose [PDF]
, 2017 Poisonings account for almost 1% of emergency room visits each year. Time is a critical factor in dealing with a toxicologic emergency. Delay in dispensing the first antidote dose can lead to life-threatening sequelae.
Brusic, V. +4 more
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Clinical Pharmacology in Drug Development, EarlyView.Abstract A pediatric‐friendly powder for oral suspension (PfOS) of tovorafenib, a type II RAF inhibitor, was developed for patients with difficulty swallowing tablets. This open‐label, randomized, phase 1 study (QSC205140) evaluated the taste/palatability of PfOS formulations (n = 12), the relative bioavailability of the PfOS versus tablet formulation,
Yang Zhang +6 more
wiley +1 more source
Antipyretic therapy in critically ill septic patients: A systematic review and meta-analysis [PDF]
, 2017 OBJECTIVE: This meta-analysis aimed to examine the impact of antipyretic therapy on mortality in critically ill septic adults. DATA SOURCES: Literature searches were implemented in Ovid Medline, Embase, Scopus, Cumulative Index of Nursing and Allied ...
Bernard +44 more
core +2 more sources
Head &Neck, EarlyView.ABSTRACT Background This study evaluates the risk of persistent opioid use (POU) among thyroidectomy patients given postoperative opioids. Methods Patients undergoing thyroidectomy were identified using the TriNetX Research Platform (2010–2024). Cohorts were divided based on opioid prescriptions on the day of surgery.
Oluwatobiloba Ayo‐Ajibola +4 more
wiley +1 more source
A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]
, 2015 Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
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