Protease inhibition, in vitro antibacterial and IFD/MM-GBSA studies of ciprofloxacin-based acetanilides. [PDF]
PLoS ONE, 2023 In this study, we have investigated ciprofloxacin-based acetanilides for their in-vitro inhibitory study against gram +ve, -ve bacteria and serine protease activity.
Rabia Akhtar +6 more
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Benzo[d]oxazoles from Anilides by N-Deprotonation–O-SNAr Cyclization [PDF]
MoleculesA synthesis of benzo[d]oxazoles by an N-deprotonation–O-SNAr cyclization sequence from anilide precursors is reported. Anilides derived from 2-fluorobenzaldehydes, activated toward SNAr ring closure by C5 electron-withdrawing groups, were prepared and ...
Nash E. Nevels +2 more
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A challenging redox neutral Cp*Co(III)-catalysed alkylation of acetanilides with 3-buten-2-one: synthesis and key insights into the mechanism through DFT calculations [PDF]
Beilstein Journal of Organic Chemistry, 2018 Traditional, established palladium cross-coupling procedures are widely applied in complex molecule synthesis; however, there is a significant disadvantage in the requirement for pre-functionalised substrates (commonly halides/triflates).
Andrew Kenny +5 more
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Direct additive-free N-formylation and N-acylation of anilines and synthesis of urea derivatives using green, efficient, and reusable deep eutectic solvent ([ChCl][ZnCl2]2) [PDF]
Scientific ReportsIn the current report, we introduce a simple, mild efficient and green protocol for N-formylation and N-acetylation of anilines using formamide, formic acid, and acetic acid as inexpensive, nontoxic, and easily available starting materials just with ...
Fatemeh Abbasi, Ali Reza Sardarian
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Coordination compounds of Cu(II) with some substituted 2-(3,5-dimethyl-pyrazol-1-yl)-methyl-acetanilides as ligands [PDF]
Journal of the Serbian Chemical Society, 2007 New complexes of Cu(II) with some substituted 2-(3,5-dimethyl-pyrazol-1-yl)-methyl-acetanilides (L) hae been synthesized. The complex compounds, CuL4X2 (where X- = Cl,Br, CH3COO) were characterized by elemental analysis, as well as IR, UV-VIS, EPR ...
Zalaru Christina +5 more
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Synthesis and Antibacterial Activity of Thymyl Ethers
Chemistry Proceedings, 2021 In this paper, we report herein a simple and efficient synthesis method of thymyl ethers for structural modifications of natural products such as monoterpenoids and studies of ether derivatives of thymol in biological importance.
Jagdish U. Patil +2 more
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Journal of Molecular Docking, 2021 Acetamides (S30A1 and S30) were synthesized from benzo[d]thiazol-2-amine and 6-nitrobenzo[d]thiazol-2-amine by direct use of acetic acid instead of acetylating agents.
Sukumar Bepary +4 more
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2,2-Dichloro-N-(3,5-dimethylphenyl)acetamide
Acta Crystallographica Section E, 2008 The structure of the title compound, C10H11Cl2NO, resembles those of 2,2-dichloro-N-phenylacetamide, 2,2-dichloro-N-(2-methylphenyl)acetamide, 2,2-dichloro-N-(3-methylphenyl)acetamide, 2,2-dichloro-N-(4-methylphenyl)acetamide, N-(3,5-dimethylphenyl ...
B. Thimme Gowda +4 more
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Pharmaceuticals, 2022 Epidermal Growth Factor Receptor (EGFR), its wild type and mutations L858R/T790M, is overexpressed in non-small cell lung cancer (NSCLC) patients and is considered an inevitable oncology target.
Moamen A. Hassanin +5 more
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Beilstein Journal of Organic Chemistry, 2018 A solvent-free palladium-catalyzed ortho-iodination of acetanilides using N-iodosuccinimide as the iodine source has been developed under ball-milling conditions. This present method avoids the use of hazardous organic solvents, high reaction temperature,
Zi Liu, Hui Xu, Guan-Wu Wang
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