Results 201 to 210 of about 18,535 (225)
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Nonlinear Model for Acetazolamide
Journal of Pharmaceutical Sciences, 1979Intravenous bolus injections of 14C-labeled acetazolamide were made in rabbits. Plasma, urine, and washed red blood cell concentrations were measured, the latter indicating bound drug. AUTOAN and NONLIN were used to fit the plasma data to a linear two-compartment model.
Albert M. Mattocks, Robert L. Kunka
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Chronic Acetazolamide Intoxication
Journal of Toxicology: Clinical Toxicology, 1984Severe acidosis associated with acetazolamide therapy is rare. We report the first case in which plasma and whole blood acetazolamide concentrations were measured. A 61 year-old patient receiving oral acetazolamide for treatment of glaucoma presented with a 7 day history of declining mental status.
James C. Garrelts +5 more
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Bioavailability of Acetazolamide Tablets
Journal of Pharmaceutical Sciences, 1978Plasma acetazolamide levels were measured by an enzymatic assay following single 250-mg oral tablet doses to 20 healthy volunteers; five different lots of acetazolamide tablets from a single manufacturer were used in a balanced incomplete block design.
Ashok C. Shah +4 more
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Acetazolamide and Outflow Facility
Archives of Ophthalmology, 1966The carbonic anhydrase inhibitors are the drugs most useful clinically in reducing aqueous flow and lowering intraocular pressure. 1-3 Their hypotensive effect is greater in the hypertensive eye than in the normal, and in the latter has been reported to be accompanied by a compensatory reduction in outflow facility.
Miles A. Galin, Laurence S. Harris
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Assay for Acetazolamide in Plasma
Journal of Pharmaceutical Sciences, 1975A method for the analysis of acetazolamide, 5-acetamido-1,3,4-thiadiazole-2-sulfonamide, sensitive to 25 ng/ml in plasma, was developed. After extraction of acetazolamide and its propionyl analog, 5-propionamido-1,3,4-thiadiazole-2-sulfonamide, the internal standard, from plasma with ethyl acetate and removal of lipids from the residue of the ethyl ...
W.F. Bayne, G. Rogers, N. Crisologo
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Sulfonamide Hypersensitivity and Acetazolamide
Archives of Ophthalmology, 1990To the Editor. —Recently, a discussion arose among the physicians in our ophthalmology residency program regarding the use of acetazolamide (Diamox, Lederle Laboratories Pearl River, NY) in patients who report a "sulfa" allergy or hypersensitivity.
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Altitude sickness and acetazolamide
BMJ, 2018### What you need to know A 25 year old man plans to trek to Everest Base Camp (5545 m) in Nepal for charity. He asks you for a prescription of acetazolamide to prevent mountain sickness. For most people, mountain sickness is a self limiting illness, but it can become life threatening.
Pippa Oakeshott +2 more
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Acetazolamide in Meniere's Disease
Archives of Otolaryngology - Head and Neck Surgery, 1957The pathologic anatomy in Meniere's disease is largely unknown. In current hypotheses, allergic, bacterial, and metabolic disturbances are considered as etiologic factors. The picture as described by Hallpike and Cairns1is that of an endolymphatic idiopathic labyrinthine hydrops, or so-called glaucoma of the labyrinth (Jenkins, Portmann, and others ...
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Acetazolamide and Exercise Hypoxia
International Journal of Sports Medicine, 2010Acetazolamide is useful for acclimatizing to high altitude. How long it should be taken, and the physiological consequences of stopping it have not been thoroughly studied. We investigated the effect of acetazolamide cessation on exercise oxygenation at different altitudes and durations of use. Three groups were studied: group 1 acclimatized to 4,060 m
D. Bartniczuk +4 more
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