Results 271 to 280 of about 846,453 (350)

Effect of Atomic Charges on C2H2/CO2/CH4 Separation Performances of Covalent‐Organic Framework Adsorbents

open access: yesAdvanced Theory and Simulations, EarlyView.
Three charge assignment approaches (one quantum chemistry method‐based, the other two machine‐learning (ML) model‐based) are employed to investigate acetylene separation performances of experimental covalent‐organic frameworks. Partial Atomic Charge Predicter for Porous Materials based on Graph Convolutional Neural Network (PACMAN) ML model‐based ...
Hakan Demir, Ilknur Erucar
wiley   +1 more source

Multivariate Screening and Automated Clustering of Macrophage Immunoreactome to Nanoparticles and Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef   +12 more
wiley   +1 more source

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

open access: yesAdvanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui   +19 more
wiley   +1 more source

Crystal structure of an aceto-nitrile solvate of 2-(3,4,5-triphen-ylphen-yl)acetic acid. [PDF]

open access: yesActa Crystallogr E Crystallogr Commun
Seidel P, Gottwald F, Meier E, Mazik M.
europepmc   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu   +10 more
wiley   +1 more source

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