Results 41 to 50 of about 797 (180)

Metal-Free SN2′ Decarboxylative Rearrangement of β-Keto Esters

, 2011
Treatment of 2-methoxycarbonyl- (or 3-cyano-)allyl acetoacetates with a tertiary amine or triphenylphosphane afforded α-methylene γ-substituted δ-keto esters (or nitrile) in satisfactory yields. Various bases and nucleophiles were tested to elucidate the
Marie-Claire Lasne, Xavier Franck, Jérôme Baudoux, Stéphane Leleu, Lasne, Marie-Claire, Vincent Bizet, Bizet, Vincent, Baudoux, Jérôme, Jacques Rouden, Leleu, Stéphane, Rouden, Jacques, Agathe Boulangé, Lefebvre, Valérie, Boulangé, Agathe, Franck, Xavier, Valérie Lefebvre   +15 more
core   +1 more source

Smart cellulose‐based room temperature phosphorescent materials: From mechanisms to construction strategies and applications

Smart Molecules, Volume 4, Issue 3, September 2026.
This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu, Yifan Zhou, Wanjin Wu, Yan Tang, Mengfan Jing, Jianyu Zhang, Haoke Zhang, Zheng Zhao, Junwei Wang, Laurent Maron, Lijie Liu   +10 more
wiley   +1 more source

Development and Application of O‑(Trimethylsilyl)aryl Fluorosulfates for the Synthesis of Arynes

, 2015
A class of o-(trimethylsilyl)­aryl fluorosulfates was synthesized by a concise method and successfully used as aryne precursors for the first time. Different trapping agents such as azides, furans, and acyl acetoacetates could successfully react with the
Li Lin (111038), Xianxing Jiang (1555024), Rui Wang (52434), Qiao Chen (641209), Hongmei Yu (584700), Zhaoqing Xu (1339896)   +5 more
core   +1 more source

Conditional eIF2A Deletion Suggests Extra‐Adipose Mechanisms Underlying Metabolic Syndrome in Total‐Body eIF2A Knockout Mice

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Adipose tissue‐specific deficiency of eIF2A is insufficient to reproduce the metabolic defects observed in total‐body eIF2A knockout mice, suggesting that the systemic metabolic effects observed in these mice may arise from coordinated functions across multiple organs.
Adedeji Isaac Adeloye, Richard Anderson, Anchal Agarwal, Barsanjit Mazumder, Taras Y. Nazarko, Atefeh Bagheri, Archana Prabahar, Peng Jiang, Frank Tedeschi, William C. Merrick, David A. Buchner, Maria Hatzoglou, Roman V. Kondratov, Anton A. Komar   +13 more
wiley   +1 more source

PECHMANN CONDENSATION OF METHYL β-RESORCYLATE WITH SOME β-KETONIC ESTERS.

, 1940
Methyl \(\beta\)-resorcylate has been condensed with ethyl \(\alpha\)-chloro and- \(\alpha\)-benzoyl aceto acetates and with ethyl acetone dicarboxylate in the presence of sulphuric acid. The results obtained show that as in the condensation of methyl \(\
S. M. SETHNA, R. C. SHAH.
core   +1 more source

Stakeholders' perspectives on integrating point‐of‐care diagnostics into forensic death investigations in South Africa

Journal of Forensic Sciences, Volume 71, Issue 5, Page 2182-2192, September 2026.
Abstract Unnatural and unexplained deaths present critical challenges to the criminal justice, medico‐legal, and public health systems. This study explored forensic professionals' perspectives on the integration of point‐of‐care (POC) diagnostics into unnatural death investigations in South Africa.
Sebueng Ramatsokotla, Bathabile Soul, Kuhlula Maluleke, Lucinda Evert, Stefan Jansen van Vurren, Bettina Chale‐Matsau, Susan Mabotja, Evans Duah, Tivani Mashamba‐Thompson   +8 more
wiley   +1 more source

Ketogenic Diet and β‐Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti‐PD‐L1 Immunotherapy Efficacy

Cancer Science, Volume 117, Issue 9, Page 2379-2396, September 2026.
Ketogenic diet and β‐hydroxybutyrate (β‐HB) suppress bladder cancer growth through direct anti‐tumor mechanisms and enhance anti‐PD‐L1 immunotherapy efficacy. β‐HB upregulates PD‐L1 via JAK2‐STAT3 activation and remodels the tumor immune microenvironment, sensitizing tumors to immune checkpoint blockade. ABSTRACT The limited clinical efficacy of immune
Yuan Zeng, Gangli Gu, Lin Yang, Bohao Fan, Haochen Cui, Lei Yan, Zhao Liu   +6 more
wiley   +1 more source

Pitfalls in 2HG Detection With TE‐Optimized MRS at 3T

Journal of Neuroimaging, Volume 36, Issue 5, September/October 2026.
ABSTRACT Background and Purpose In vivo MRS of 2‐hydroxyglutarate (2HG) may provide diagnostic and monitoring biomarkers in isocitrate dehydrogenase (IDH)‐mutated glioma. A previous meta‐analysis has shown good diagnostic accuracy of TE‐optimized PRESS for IDH‐mutated glioma, but most studies feature IDH‐wildtype glioma as a comparison.
Seyma Alcicek, Dunja Simicic, Lindsay Blair, Max Saint‐Germain, Helge J. Zöllner, Christopher W. Davies‐Jenkins, Matthias Holdhoff, John Laterra, Chetan Bettegowda, Karisa C. Schreck, Doris D. Lin, Peter B. Barker, David O. Kamson, Georg Oeltzschner   +13 more
wiley   +1 more source

Synthesis and spectral properties of substituted 1,4-dihydropyridines and 1,4,5,6,7,8-hexahydroquinolines

, 1987
Cyclocondensation of 5-nitrophenyl-2-furaldehydes or 5-nitrophenyl-2-thiophenecarbaldehydes with acetoacetates and ammonia in organic solvents afforded 1,4-dihydropyridine derivatives, with 3-aminocrotonates and dimedone the former yielded 1,4,5,6,7,8 ...
Pavol Čupka, Juraj Bella, Augustin Martvoň   +2 more
core   +1 more source

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

Plant Biotechnology Journal, Volume 24, Issue 9, Page 5131-5151, September 2026.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng, Huan Li, Jun Wang, Li‐Chao Wang, Hui‐Zi Liu, Xiao‐Feng Dai, Steven J. Klosterman, Jie‐Yin Chen, Krishna V. Subbarao, Feng‐Mao Chen, Dan‐Dan Zhang   +10 more
wiley   +1 more source