Results 31 to 40 of about 797 (180)
The chemical features, such as substrate stability, product distribution, and substrate generality, and the reaction mechanism of Brønsted superacid-catalyzed cyclization reactions of aromatic ring-containing acetoacetates (β-ketoesters) were examined in
Hiroaki Kurouchi (2032846) +3 more
core +1 more source
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts +8 more
wiley +1 more source
Dihydropyrimidines were synthesised in high yields by one-pot cyclocondensation reaction of aldehydes, acetoacetates and urea using various acid catalysts like Amberlyst-15, Nafion-H, KSF clay and dry acetic acid under microwave ...
Jagan Reddy, E. +3 more
core +1 more source
Ferrimyoglobin pseudoperoxidase activity was demonstrated during isobutyraldehyde oxidation, yielding electronically excited triplet acetone and inducing structural damage. Sorbates and 9,10‐dibromoanthracene‐2‐sulfonate exhibited protective effects.
Thiago M. V. Gomes +4 more
wiley +1 more source
The Thermal Inactivation of Acetoacetate Decarboxylase
Abstract The acetoacetate decarboxylase obtained from Clostridium acetobutylicum undergoes a biphasic thermal inactivation; the rapid phase of which was temperature sensitive, whereas the slow phase was much less so. ΔHa for the rapid phase of inactivation was 49 kcal per mole.
A P, Autor, I, Fridovich
openaire +2 more sources
This study designed and synthesized dithioacetal‐modified dihydropyrimidinone derivatives (30). Compound D3 showed optimal anti‐inflammatory activity, inhibiting the MAPK/NF‐κB pathway, reducing NO secretion (IC50 = 1.2 µM), and ameliorating DSS‐induced acute colitis in mice, offering a new candidate for inflammatory bowel disease therapy.
Jian‐Wei Jiang +6 more
wiley +1 more source
Abstract Objective Ketogenic dietary therapies can reduce seizure frequency in drug‐resistant epilepsy, but adherence to the classical ketogenic diet is often poor. Intermittent fasting supplemented with medium‐chain triglycerides (MCTs) may offer a more feasible and less restrictive alternative.
Wiebke Hahn +11 more
wiley +1 more source
Isoxazoline-containing peptidomimetics, designed to be effective α vβ 3 and α 5β 1 integrin ligands, were synthesized through an original procedure involving N,O-bis(trimethylsilyl)hydroxyamine conjugate addition to alkylidene acetoacetates, followed by ...
SPAMPINATO, SANTI MARIO +24 more
core +1 more source
Amino Acid Metabolism in Health and Disease
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su +7 more
wiley +1 more source
A Review on Green Synthetic Approaches in the Development of Quinoline Analogues
This review highlights recent advances in environmentally friendly approaches, including metal‐free systems, solvent‐free approaches, microwave, and ultrasonic‐assisted techniques, organo‐ and biocatalysis, ionic liquids, nanoparticle catalysis, electrochemical, and photocatalytic strategies for the synthesis of quinoline scaffolds.
Demis Zelelew +3 more
wiley +1 more source

