Results 11 to 20 of about 11,118 (177)

Lithium and Not Acetoacetate Influences the Growth of Cells Treated with Lithium Acetoacetate [PDF]

International Journal of Molecular Sciences, 2019
The ketogenic diet (KD), a high-fat/low-carbohydrate/adequate-protein diet, has been proposed as a treatment for a variety of diseases, including cancer. KD leads to generation of ketone bodies (KBs), predominantly acetoacetate (AcAc) and 3-hydroxy-butyrate, as a result of fatty acid oxidation. Several studies investigated the antiproliferative effects
Vidali, Silvia, Aminzadeh-Gohari, Sepideh, Vatrinet, Renaud, Iommarini, Luisa, Porcelli, Anna Maria, Kofler, Barbara, Feichtinger, René Günther   +6 more
openaire   +4 more sources

Acetoacetate and ethyl acetoacetate as novel inhibitors of bacterial biofilm [PDF]

Letters in Applied Microbiology, 2018
Acetoacetate (AAA) was identified as a biofilm inhibitor in a previous study, where the effect of 190 carbon and nitrogen sources on biofilm amounts by Escherichia coli O157:H7 was determined. With this study, we tested the effect of AAA on growth and biofilm amounts of Cronobacter sakazakii, Serratia marcescens and Yersinia enterocolitica. AAA reduced
S M, Horne, M, Schroeder, J, Murphy, B M, Prüβ   +3 more
openaire   +2 more sources

The Conversion of Acetoacetate to Pyruvaldehyde

Journal of Biological Chemistry, 1967
Abstract The oxidative decarboxylation of acetoacetate to pyruvaldehyde is catalyzed by sheep heart extracts in the presence of O2 and Mn2+. The product was identified by spectral and chromatographic methods. From fractionation and inhibitor characteristics and the similarity of the catalytic activity to that of commercial myoglobin, it is concluded ...
L P, Milligan, R L, Baldwin
openaire   +2 more sources

High‐Strength, Fluorescent, Triboelectric Cellulose Hydrogel‐Derived Plastics Through Molecular Network Engineering for Energy Harvesting and Motion Sensing

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Multifunctional cellulose hydrogel‐derived plastics (FCBPs) are fabricated via a novel molecular network engineering strategy involving epoxy cross‐linking, solvent exchange, and hot‐pressing techniques. The resulting materials exhibit high mechanical strength, excellent thermal/solvent resistance, stable fluorescence, complete biodegradability, and ...
Fuyuan Lu, Yifan Jiao, Yuxuan Chen, Zhezhe Zhou, Gaobo Lou, Caicai Li, Gaojie Jiao, Mark Lynch, Jialong Wen, Xiaochun Zhang, Pingan Song, Dan Sun   +11 more
wiley   +1 more source

I.—Ethylic phenanthroxylene-acetoacetate [PDF]

J. Chem. Soc., Trans., 1891
n ...
Japp, Francis R., Klingemann, Felix
openaire   +2 more sources

Intermittent fasting with medium‐chain triglycerides in drug‐resistant epilepsy: A pilot crossover trial

Epilepsia, EarlyView.
Abstract Objective Ketogenic dietary therapies can reduce seizure frequency in drug‐resistant epilepsy, but adherence to the classical ketogenic diet is often poor. Intermittent fasting supplemented with medium‐chain triglycerides (MCTs) may offer a more feasible and less restrictive alternative.
Wiebke Hahn, Emily Falk, Ayla Balzter, Tobias Foer, Shanin Maierhofer, Sophia Jaumann, Sascha Strehlau, Leona Möller, Panagiota‐Eleni Tsalouchidou, Katja Menzler, Lars Timmermann, Susanne Knake   +11 more
wiley   +1 more source

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

Epilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi, John Williamson, Jhanvi Patel, Samikksha Kumar, Huayu Sun, Lucy Dang Nguyen, Katarzyna Rękawek, Ifrah Zawar, Jaideep Kapur   +8 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Robust β‐myrcene block copolymer elastomeric vitrimers

Polymer International, EarlyView.
Myrcene‐based vitrimeric elastomers were compared: statistical (poly(styrene‐stat‐myrcene‐stat‐AAEMA)] versus ‘hard–soft’ diblock (poly(styrene)‐block‐poly(myrcene‐co‐AAEMA)). The diblock's ability to anchor the glassy poly(styrene) blocks in a self‐assembled microstructure was effective – leading to four times higher tensile stress and ten times ...
Chong Yang Du, Farhad Asempour, Milan Marić   +2 more
wiley   +1 more source

Smart cellulose‐based room temperature phosphorescent materials: From mechanisms to construction strategies and applications

Smart Molecules, EarlyView.
This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu, Yifan Zhou, Wanjin Wu, Yan Tang, Mengfan Jing, Jianyu Zhang, Haoke Zhang, Zheng Zhao, Junwei Wang, Laurent Maron, Lijie Liu   +10 more
wiley   +1 more source