Results 51 to 60 of about 8,297 (181)

Metabolic Flux and Growth Profiling of Megasphaera cerevisiae for Medium‐Chain Fatty Acid Synthesis

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Characterising the metabolism of medium‐chain fatty acids in Megasphaera cerevisiae, based on genome‐scale metabolic modelling and integration with experimental data obtained from controlled bioreactor cultivations. The iterative approach aligns in silico predictions with empirical observations and a refined model was obtained.
Wael Sabra, Sonia Villotti, Joachim Fensterle, An‐Ping Zeng, Ahmed M. Haddad   +4 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, Volume 16, Issue 7, Page 1314-1327, July 2026.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

Enantioselective Synthesis of Lactic Acid From CO2 Using a Novel Pyruvate Decarboxylase in a Scalable Biocatalytic Cascade

Advanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
We report a scalable biocatalytic cascade that converts CO2 and acetaldehyde to pyruvate via a newly characterized pyruvate decarboxylase, followed by stereoselective reduction to lactic acid. The system enables fully switchable enantioselectivity using either L‐ or D‐lactate dehydrogenases.
Silvia Fruncillo, Daan M. van Vliet, Jurgen J. Mateman, Dirk C. van Seijst, Jan Stoutjesdijk, Jason van Rooyen, Akash Pandya, James Galman, Annette Alcasabas, Tom A. Ewing   +9 more
wiley   +1 more source

Fermented Plant‐Based Milks: A Review of Physicochemical and Technological Aspects to Sensory and Probiotic Attributes

Food Bioengineering, Volume 5, Issue 2, Page 314-334, June 2026.
Technological and biotechnological processes, including fermentation with selected starter cultures, convert diverse plant raw materials into fermented plant‐based milks. These processes enhance nutritional profiles, functional and probiotic compounds, and improve physicochemical and sensory properties, supported by predictive modeling to optimize ...
Luiz Henrique de Oliveira Cruz, Raíssa Machado Nascimento, Alice Gonçalves Martins Gonzalez, Josiane Roberto Domingues   +3 more
wiley   +1 more source

Production and Multi‐Criteria Evaluation of Healthy White Cheese Snacks Using Microwave‐Vacuum Drying

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Microwave‐assisted vacuum drying (MVD) is an emerging technology suitable for producing healthy snack foods, such as cheese snacks. This study aimed to produce a low‐fat, low‐salt, crunchy cheese snack using MVD. Low‐fat, low‐salt cheese slices were dried under seven different combinations of microwave power (5%–15%), vacuum level (220–300 ...
Vasıf Kubilay Ayrancı, Mondher Mzoughi, Pelin Salum, Tuba Eda Arpa Zemzemoğlu, Zafer Erbay   +4 more
wiley   +1 more source

Microbial Community Shifts and Plant Performance Improvements Driven by Bacillus firmus in Pampa Agroecosystems

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The study shows that Bacillus firmus‐based bionematicides modulate soil microbiota and enhance soybean growth in the Pampa biome. Effects vary by location and time, with increased beneficial bacteria, reduced fungi, and decreased root nematode infestation. Overall, B.
David Fagundes, Laís Mara Santana Costa, Alexandro Cagliari, Diego Prado de Vargas, Alexandre Rieger   +4 more
wiley   +1 more source

Nanobiocatalysts: Potential Applications in Biofuel Production and Biotransformation

Carbon Neutralization, Volume 5, Issue 3, May 2026.
The application of nanobiocatalysts in the field of biofuel production and the biotransformation of substrate were reviewed. Further, the possible research gaps in the field of biofuel and value‐added compound production and a possible way to enhance the application of nanobiocatalyst in future development are highlighted.
Preethi Muthu, Kalaiselvi Thiyagarajan, V. Pugalenthi, M. Gunasekaran, J. Rajesh Banu   +4 more
wiley   +1 more source

Milk‐Clotting Protease From Bacillus stercoris NCCP‐3139: A Potential Microbial Rennet for Cheese Production

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
A milk‐clotting protease from Bacillus stercoris NCCP‐3139 was isolated from soil and purified via ammonium sulfate precipitation and sequential chromatographic techniques, yielding a homogeneous enzyme confirmed by SDS–PAGE. The protease exhibited high catalytic selectivity, with a marked increase in milk‐clotting‐to‐proteolytic activity ratio (50–550)
Muhammad Sibtain, Ashraf Ahmed Qurtam, Sadaf Javaria, Ghulam Murtaza, Mohammed Al‐zharani, Noor‐ul Ain, Sadia Chaman, Fahd A. Nasr, Ali Zaman   +8 more
wiley   +1 more source

A ‘Genome‐First’ Framework for Next‐Generation Bioinputs: From Functional Mining to Rational Synthetic Microbial Communities

Environmental Microbiology, Volume 28, Issue 5, May 2026.
I propose a ‘genome‐first’ framework to collapse the phenotypic bottleneck in bioinput discovery. By integrating multi‐layered genome mining and reverse ecology, this paradigm enables the rational design of stable synthetic microbial communities for a data‐driven and sustainable agricultural bioeconomy.
Osiel Silva Gonçalves
wiley   +1 more source