Results 31 to 40 of about 239 (169)

Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles

Advanced Science, EarlyView.
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu, Youzhi Xu, Weitao Zhang, Yongyue Ning, Yaojia Jiang, Yongquan Ning, Genping Huang, Jiawei Cheng, Paramasivam Sivaguru, Xihe Bi   +9 more
wiley   +1 more source

Detoxification of host plant phenolic aglycones by the spruce budworm.

PLoS ONE, 2019
This study examines the post-ingestive fate of two host-plant derived small-molecule phenolics (the acetophenones piceol and pungenol) that have previously been shown to be toxic to the outbreaking forest pest, spruce budworm (Choristoneura fumiferana ...
Dominic Donkor, Zahra Mirzahosseini, Jacquie Bede, Eric Bauce, Emma Despland   +4 more
doaj   +1 more source

Improving the Physicochemical Properties, Organic Acids, Amino Acids, Volatile Organic Compounds, and Metabolites of Laohan Melon Juice Through Fermentation With Different Lactic Acid Bacteria

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermentation with lactic acid bacteria could improve amino acids, volatile organic compounds (VOCs), and nonvolatile metabolites of Laohan melon juice (LMJ), which provides theoretical guidance for the development of Laohan melon beverage and advances knowledge of the metabolic mechanisms of VOCs in LMJ.
Yun Xie, Sihan Hou, Mingdong Tan, Jianqiao Jiang, Yue Hu, Yiwen Chen, Yongkang Li, Miao Cui, Jianming Niu, Weidong Cheng, Xilei Pu, Yuyun He, Feifei Gao   +12 more
wiley   +1 more source

Aromatic C-H addition of ketones to imines enabled by manganese catalysis

Nature Communications, 2017
The Mannich reaction proceeds by functionalization of C(sp3)-H bonds alpha to carbonyls. Here, the authors suppress the Mannich reactivity of acetophenones in presence of a manganese catalyst and obtain valuable o-aminoalkylacetophenones and isoindolines
Bingwei Zhou, Yuanyuan Hu, Ting Liu, Congyang Wang   +3 more
doaj   +1 more source

Acetophenones with selective antimycobacterial activity [PDF]

Letters in Applied Microbiology, 2005
Mycobacteria are a serious cause of infections in humans, with limited treatment options, as no new antibiotics have been developed against mycobacteria since the 1960s. In this study, the antimycobacterial activity of a small library of acetophenone (AP) compounds was analysed.Twenty-three AP derivatives were examined for activity against mycobacteria
L, Rajabi, C, Courreges, J, Montoya, R J, Aguilera, T P, Primm   +4 more
openaire   +2 more sources

Katalytische C–F‐Aktivierung bei Raumtemperatur: Enolat Kreuzkupplungen ermöglicht durch [Pd(1‐MeNAP)TFA]2 / LiHMDS

Angewandte Chemie, EarlyView.
Katalysatoren, die aus dem Trifluoroacetat‐verbrückten Methylnaphthyl‐Palladium‐Dimer [Pd(1‐MeNAP)TFA]2 und Biarylphosphin‐Liganden generiert werden, in Kombination mit der Base LiHMDS, fördern α‐Arylierungsreaktionen verschiedener Enolate mit nicht‐aktivierten Arylfluoriden bei Raumtemperatur.
Nele Krüger, Jie Shen, Sourav Manna, Lamphiza O. Najiar, Lukas J. Gooßen   +4 more
wiley   +1 more source

Synthesis and Spectroscopic Investigation of Some New Chalcones and their transformation to pyrazoline derivatives [PDF]

Kirkuk Journal of Science, 2012
A series of a new chalcone derivatives (2a-i) containing benzyloxy moiety have been synthesized on the basis of base catalyzed claisen –Schmidt condensation in high yields from the reaction of the prepared starting material 3-(4-cholrobenzyloxy ...
Shakhawan A. Omer, Muhamad S. Ahmad, Farouq E. Hawaiz   +2 more
doaj   +1 more source

Catalytic C–F Bond Activation at Room Temperature: Enolate Cross‐Couplings Enabled by [Pd(1‐MeNAP)TFA]2 and LiHMDS

Angewandte Chemie International Edition, EarlyView.
Catalysts generated from the trifluoroacetate‐bridged methylnaphthyl‐palladium dimer [Pd(1‐MeNAP)TFA]2 and biarylphosphine ligands in combination with the base LiHMDS promote α‐arylation reactions of various enolates with non‐activated aryl fluorides at room temperature.
Nele Krüger, Jie Shen, Sourav Manna, Lamphiza O. Najiar, Lukas J. Gooßen   +4 more
wiley   +1 more source

Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria

Food Technology and Biotechnology, 2008
Whole cells of hydrocarbon-degrading bacteria, isolated from polluted sediments in the Santos Estuary (Baixada Santista, São Paulo, Brazil), were able to catalyse oxidoreduction reactions with various substituted phenylethanols and acetophenones as ...
Edna Kagohara, Vivian Helena Pellizari, João Valdir Comasseto, Leandro Helgueira Andrade, André Luiz Meleiro Porto   +4 more
doaj  

Acetophenones Isolated from and their Anti-proliferative Activities

Natural Product Communications, 2016
Study of the chemical constituents of Acronychia pedunculata (L.) Miq. (Rutaceae) stems collected in Taiwan led to the isolation and identification of eight known and three new acetophenones, named acrophenone A ( 1 ), B ( 2 ), and C ( 3 ).
Chihiro Ito, Takuya Matsui, Yoshiaki Ban, Tian-Shung Wu, Masataka Itoigawa   +4 more
doaj   +1 more source