Results 161 to 170 of about 199,012 (297)

ACSS2/AATF Drives Soluble FasL‐Mediated CD8+ T Cell Apoptosis in Pancreatic Neuroendocrine Tumors

Advanced Science, EarlyView.
This study unveils that ACSS2‐driven acetate metabolism fuels histone pan‐acetylation in pancreatic neuroendocrine tumors (PNETs), remodeling the epigenetic landscape. The ACSS2/AATF axis transcriptionally activates soluble FasL (sFasL), which engages Fas receptors on infiltrating CD8+ T cells to trigger caspase‐8/3‐mediated apoptosis.
Qin Dang, Ting Wang, Yan Wang, Zeng Ye, Borui Li, Xuan Pan, Zheng Li, Guixiong Fan, Desheng Jing, Junfeng Xu, Qiangsheng Hu, Shunrong Ji, Xiaowu Xu, Xianjun Yu, Yi Qin   +14 more
wiley   +1 more source

SAT1 promotes the progression of OA by regulating TRIM33-mediated p53 acetylation to enhance ferroptosis. [PDF]

PLoS One
Yang J, Jiang J, Wang J, Luo L.
europepmc   +1 more source

On the Studies of Reactivity of Pulps for Acetylation

, 1956
Saburō Ishikawa
openalex   +2 more sources

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
wiley   +1 more source

From allergens to epigenetics: how histone acetylation shapes immune gene expression in allergic diseases. [PDF]

Epigenomics
Cai X, Afthab M, Hambo S, Salem M, Bhitale RR, Harb H.   +5 more
europepmc   +1 more source

LIQUID PHASE FIBROUS ACETYLATION OF CELLULOSE

, 1957
Ichiro Sakurada, Yasuyoshi Sakaguchi, Kazuhiro Nagai   +2 more
openalex   +2 more sources

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression

Advanced Science, EarlyView.
An et al. reveal H3K27ac elevation is essential for establishing and maintaining human naive pluripotency; its inhibition disrupts this state while enhancement promotes it. METTL3‐mediated m6A modification indirectly controls H3K27ac by suppressing EP300 expression. Reduced EP300 lowers H3K27ac, impeding naive pluripotency.
Chenrui An, Ke Zhong, Xiangjin Kang, Yingying Zhang, Yudan Shang, Hao Liu, Yushan Ji, Jinbei Zeng, Jiajin Lin, Long Jin, Zelong Lin, Yang Yu, Xuetao Shi, Yong Fan   +13 more
wiley   +1 more source

MRPL12 K163 acetylation inhibits ccRCC via driving mitochondrial metabolic reprogramming. [PDF]

Cell Death Dis
Ji X, Xue F, Wang Y, Gao D, Sun J, Dong T, Mu Q, Xu Q, Sun S, Liu Y, Wan Q.   +10 more
europepmc   +1 more source

STUDIES ON THE VAPOUR PHASE ACETYLATION OF CELLULOSE

, 1955
Iichiro Kido, Kimihiro Suzuki, Taro Yamada   +2 more
openalex   +2 more sources

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source