Results 301 to 310 of about 374,029 (398)

Acetylation of Tetrodotoxin

open access: bronze, 1964
Toshio Goto   +3 more
openalex   +2 more sources

Enantiomerically Enriched Aziridine‐2‐carboxylates via Copper‐Catalyzed Reductive Kinetic Resolution of 2H‐Azirines

open access: yesAngewandte Chemie, EarlyView.
Kinetic resolution by copper hydride catalyzed reduction of 2H‐azirines secured optically enriched N‐H aziridine‐2‐carboxylates with excellent diastereoselectivity (>20:1) and good enantioselectivity (up to 94% ee). DFT calculations and non‐covalent interaction analysis established the reaction pathway and revealed two key non‐covalent interactions ...
Yinuo Zheng   +3 more
wiley   +2 more sources

Phenotypic Characterization of Seven Pediatric Patients Diagnosed With KAT6B‐Related Disorders: Case Series and Review of the Literature

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genitopatellar syndrome (GPS) and Say‐Barber‐Biesecker‐Young‐Simpson Syndrome (SBBYSS) are clinically distinct neurodevelopmental disorders caused by monoallelic pathogenic variants in KAT6B. In some cases, GPS and SBBYSS features can overlap, determining an intermediate phenotype.
Vittorio Maglione   +12 more
wiley   +1 more source

Deacetylation of nuclear AIF provides a braking mechanism for caspase-independent chromatinolysis and necrotic brain injury. [PDF]

open access: yesCommun Biol
Hu C   +13 more
europepmc   +1 more source

RNA Binding to CBP Stimulates Histone Acetylation and Transcription

open access: yesCell, 2017
D. Bose   +5 more
semanticscholar   +1 more source

On‐Demand Ligate and Release Strategy Based on Photoclick Reaction in Tandem with Pd‐Mediated Deallylation

open access: yesAngewandte Chemie, EarlyView.
A consecutive, controllable, and revertible new‐to‐nature ligation and cleavage strategy has been rationally devised to selectively visualize and manipulate biomolecules of interest. The photoclick cycloaddition between allenyl phenyl ether motifs and 9,10‐phenanthrenequinone analogues installed a terminal allyl handle at the exocyclic site, thereby ...
Boon Shing Loh   +4 more
wiley   +2 more sources

Synthesis of 2H‐1,4‐Oxazin‐3(4H)‐One Utilizing Umpolung Reaction to α‐Hydrazonoketone

open access: yesAsian Journal of Organic Chemistry, Volume 14, Issue 3, March 2025.
An Efficient Method of the Synthesis of a 2H‐1,4‐Oxazin‐3(4H)‐One via the Tandem N‐Alkylation/Reduction/N‐Acyl‐O‐Alkylation of α‐Hydrazonoketone Has Been Developed. This Reaction Proceeds Extremely Quickly Under Mild Conditions, in Particular, N‐Methylation Proceeds Quantitatively, Which Was Difficult to Achieve by Conventional Umpolung N‐Alkylation ...
Isao Mizota   +7 more
wiley   +1 more source

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