Results 141 to 150 of about 221,231 (306)
Journal of Applied Toxicology, EarlyView.ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley +1 more source
Neuromuscular: Acetylcholine and Acetylcholine Receptors
, 2006 The Neuromuscular Disease Center at Washington University provides this comprehensive Web site for information on acetylcholine and acetylcholine receptors. Visitors will find detailed Web pages covering acetylcholine metabolism, acetylcholine receptors (
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Journal of Clinical Laboratory Analysis, EarlyView.Distal 1q43q44 deletions lead to a consistent neurodevelopmental phenotype characterized by microcephaly, corpus callosum abnormalities, and developmental delay. Despite differences in genomic architecture, overlapping deletions affecting dosage‐sensitive genes such as AKT3, HNRNPU, and ZBTB18 define the core phenotype.
Ma. Guadalupe Domínguez‐Quezada +6 more
wiley +1 more source
Journal of Clinical Ultrasound, EarlyView.Diaphragm ultrasonography detected progressive structural and functional deterioration in mechanically ventilated children. Prolonged invasive mechanical ventilation and neuromuscular blocking agent use were associated with ventilator‐induced diaphragmatic dysfunction, highlighting ultrasound as a valuable bedside tool to support individualized ...
Juliana Bezerra dos Santos +3 more
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho +6 more
wiley +1 more source
, 1998 Introduction of the #4 residues 183--191 into #7 subunit sequence (chimera C 2 ) selectively increased the apparent affinities for equilibrium binding and for ion channel activation by acetylcholine, resulting in a receptor that no longer displays ...
Stuart J. Edelstein +7 more
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Intraoperative Bradycardia: Evaluating Vasovagal Events in Adult Suspension Microlaryngeal Surgery
The Laryngoscope, EarlyView.This retrospective single‐surgeon cohort study of 190 adults undergoing suspension microlaryngoscopy found that 8.9% (17/190) developed significant intraoperative bradycardia consistent with a vasovagal response (VVR). No demographic, comorbidity, or procedural factors were significantly associated with VVR, though most affected patients required ...
Thomas Q. McClelland +4 more
wiley +1 more source