Results 211 to 220 of about 227,192 (263)

Cystic Thymoma-Associated Fulminant Myasthenia Gravis with Rapid Progression in a Cat: Diagnostic and Therapeutic Challenges. [PDF]

Vet Sci
Park JH, Byun GU, Lee JW, Kim DH, Jung DI, Lee D, Moon CH.   +6 more
europepmc   +1 more source

Cholinergic inputs to motoneurons in the spinal cord augment focal muscle spasticity in rodents

British Journal of Pharmacology, EarlyView.
Background and Purpose Cholinergic premotor inputs to motoneurons support high levels of motor output when required. However, the possible role of these inputs in pathologically elevated muscle tone has not been characterised. To address this, we examined the modulatory effect of spinal acetylcholine (ACh) on experimental spastic paralysis ...
Patrik Meglić, Petra Šoštarić, Eirini Tsape, Melpomeni Galani, Ana Knezović, Laura Restani, Marco Pirazzini, Ornella Rossetto, Gareth B. Miles, Laskaro Zagoraiou, Ivica Matak   +10 more
wiley   +1 more source

The Serotonergic and Cholinergic Signaling Pathways Drive Gastric Precancerous Lesions and Its Potential Mechanism

Cancer Science, EarlyView.
Vagal cholinergic neurons promote gastric 5‐HT secretion, which drives gastric precancerous lesions through 5‐HTR1D and TRPV4, highlighting these as candidate targets for early intervention. ABSTRACT Gastric cancer (GC) is a leading lethal malignancy globally. Gastric precancerous lesion (GPL) represents a critical step in GC, but its neural regulatory
Shengli Gao, Xufei Feng, Nana Zhang, Jia Su, Yuyan Wang, Linghan Kong, Jianing Zhou, Hui Dong, Feifei Guo   +8 more
wiley   +1 more source

Clinical Presentation and Treatment Response in Women With Acetylcholine-Confirmed Coronary Spasm: A Single-Center Observational Study. [PDF]

Clin Cardiol
Sikulu J, Kubini R, Turkman M, Immohr MB, Becker M, Zayat R, Aljalloud A.   +6 more
europepmc   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

Methods for measuring neural activity during voluntary wheel running. [PDF]

J Neurosci Methods
Letsinger AC, Ochoa BN, Wu JJ, Tang KU, Youngstrom D, Wang S, Bridge M, Cui G, Yakel JL.   +8 more
europepmc   +1 more source

A 1% glycopyrronium bromide cream for topical treatment of severe primary axillary hyperhidrosis in adolescents: safety, local tolerability, systemic exposure and efficacy from an open‐label phase II study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Primary axillary hyperhidrosis (PAHH) results from dysregulation of the autonomic nervous system and typically begins during puberty. Treatment options for adolescents remain limited. This open‐label phase II study evaluated the safety, local tolerability, systemic exposure, and efficacy of 1% GPB cream over 8 weeks in
Rolf‐Markus Szeimies, Ana Kilic, Hubert Reich, Birgit Berger, Erik Schulze zur Wiesche, Leonie Litzka, Katharina Schramm, Susanne Heimstaedt‐Muskett, Clarissa Masur   +8 more
wiley   +1 more source

Focal Myocardial Fibrosis Mimicking Hypertrophy in INOCA and the Energetic Cost of Supranormal Ejection Fraction. [PDF]

JACC Case Rep
Nguyen TH, Nakamura T, Sato A.
europepmc   +1 more source

Assessing Predator Activity on Clay Models in Response to Common Insecticides in Turfgrass

Entomologia Experimentalis et Applicata, EarlyView.
Insecticides exhibited clear but time‐dependent effects on predatory activity, as reflected by impression types and density on clay models in turfgrass. Certain insecticides (bifenthrin, and in some cases acephate + imidacloprid, imidacloprid, chlorantraniliprole, and tetraniliprole) reduced total impressions shortly after application and again later ...
Mahesh Ghimire, Shimat V. Joseph
wiley   +1 more source