Results 221 to 230 of about 154,788 (267)
Some of the next articles are maybe not open access.
Nature, 1953
A STUDY of two species of blowfly, Calliphora erythrocephala and Lucilia sericata, has shown that a rapid synthesis of an acetylcholine-like substance can take place in extracts prepared from these insects. This synthesis, which occurs in the absence of additional substrate, may account for some of the high concentrations of acetylcholine which have ...
openaire +2 more sources
A STUDY of two species of blowfly, Calliphora erythrocephala and Lucilia sericata, has shown that a rapid synthesis of an acetylcholine-like substance can take place in extracts prepared from these insects. This synthesis, which occurs in the absence of additional substrate, may account for some of the high concentrations of acetylcholine which have ...
openaire +2 more sources
Acetylcholine Binding Site in the Vesicular Acetylcholine Transporter
Biochemistry, 2004This study sought primarily to locate the acetylcholine (ACh) binding site in the vesicular acetylcholine transporter (VAChT). The design of the study also allowed us to locate residues linked to (a) the binding site for the allosteric inhibitor vesamicol and (b) the rates of the two transmembrane reorientation steps of a transport cycle.
Ana M, Ojeda +2 more
openaire +2 more sources
Acta Physiologica Scandinavica, 1951
Summary.In the non‐atropinized cat small doses of acetylcholine stimulate respiration practically only by lowering the blood pressure, thereby causing local oxygen want within the carotid and aortic bodies. With somewhat larger doses (0.2 mg) there is also a direct stimulation of the chemoreceptors as well as an inhibition of the centre and a ...
openaire +2 more sources
Summary.In the non‐atropinized cat small doses of acetylcholine stimulate respiration practically only by lowering the blood pressure, thereby causing local oxygen want within the carotid and aortic bodies. With somewhat larger doses (0.2 mg) there is also a direct stimulation of the chemoreceptors as well as an inhibition of the centre and a ...
openaire +2 more sources
Action of acetylcholine on rabbit auricles in relation to acetylcholine synthesis
The Journal of Physiology, 1949WHEN the heart is removed from a freshly killed rabbit, the auricles can be dissected and put in a bath of Tyrode solution at 28° C. in which they continue to beat. The addition of acetylcholine to the bath slows the rate and diminishes the amplitude of the contractions.
E, BULBRING, J H, BURN
openaire +5 more sources
Quarterly Reviews of Biophysics, 1974
The idea that certain drugs and neurotransmitters produce their effects by combining with specific receptors was first clearly expressed by Langley (1905) on the basis of the selective and localized effect of nicotine on striated muscle fibres. In 1914, Langley published a paper in which the antagonism between ‘curari’ and nicotine ...
openaire +2 more sources
The idea that certain drugs and neurotransmitters produce their effects by combining with specific receptors was first clearly expressed by Langley (1905) on the basis of the selective and localized effect of nicotine on striated muscle fibres. In 1914, Langley published a paper in which the antagonism between ‘curari’ and nicotine ...
openaire +2 more sources
ACETYLCHOLINE AND CHOLINE ACETYLTRANSFERASE
Neurochemistry International, 1980The thermodynamics and kinetics of the alcoholysis of thiolesters are discussed and related to choline acetyltransferase. The conformation and rotational barriers of acetylcholine are described as is the specific inability of choline to induce depolarization. Evidence is presented for the involvement of imidazole and the non-involvement of thiol groups
openaire +2 more sources
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor
Cell, 2021Anant Gharpure +2 more
exaly