Results 261 to 270 of about 343,067 (338)

Chinese expert consensus on intranasal anticholinergics for allergic rhinitis. [PDF]

open access: yesAsia Pac Allergy
Li X   +26 more
europepmc   +1 more source

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell   +4 more
wiley   +1 more source

Nipocalimab Dose Selection in Generalized Myasthenia Gravis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Model‐Informed Nipocalimab Dose Selection for Generalized Myasthenia Gravis. ABSTRACT Nipocalimab is a fully human immunoglobulin G (IgG)1 monoclonal antibody (mAb) designed to selectively block the IgG binding site of neonatal fragment crystallizable receptor (FcRn) to inhibit IgG recycling and decrease circulating IgG, including pathogenic IgG ...
Belén Valenzuela   +8 more
wiley   +1 more source

Effect of Hewei Anshen Decoction on depressive insomnia and brain neurotransmitter levels

open access: yesSleep Research, EarlyView.
Abstract Objective To evaluate the therapeutic effect of Hewei Anshen Decoction (HAD) on both depressive symptoms and sleep quality in patients with depressive insomnia, and to investigate its impact on brain neurotransmitter levels. Methods Seventy‐two patients with depressive insomnia were randomly assigned to a treatment group and a control group ...
Feifei Lv   +4 more
wiley   +1 more source

Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation

open access: yesSmall Science, EarlyView.
Tregs control immune tolerance but can also enable tumor escape. Nanomaterials can now expand or stabilize Tregs to treat autoimmunity and support transplantation or conversely disrupt tumor Tregs to boost antitumor immunity. We also discuss unintended Treg modulation by nanoparticles, safety and manufacturing challenges, and future translational ...
Yiyin Chen   +10 more
wiley   +1 more source

Non-neuronal cholinergic stimulation favors bone mass accrual. [PDF]

open access: yesFront Physiol
Tamimi F   +7 more
europepmc   +1 more source

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