Results 121 to 130 of about 124,177 (265)

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

Differential inhibition of the release of endogenous and newly synthesized acetylcholine from Torpedo synaptosomes by presynaptic muscarinic receptors [PDF]

, 1983
Shira Luz, Irit Pinchasi, Daniel M. Michaelson   +2 more
openalex   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Back Cover: Insight into the Binding Mode of Agonists of the Nicotinic Acetylcholine Receptor from Calculated Electron Densities (ChemPhysChem 13/2015) [PDF]

, 2015
Michael E. Beck, Oliver Gutbrod, Svend Matthiesen   +2 more
openalex   +1 more source

Pediatric intestinal pseudo‐obstruction found in 3‐year‐old male with Rett‐related mutation of methyl‐CpG binding protein 2

JPGN Reports, EarlyView.
Abstract A 3‐year‐old male with chronic abdominal distention, constipation, and severe malnutrition is diagnosed with pediatric intestinal pseudo‐obstruction (PIPO) after extensive evaluation that excluded mechanical, malabsorptive, metabolic, inflammatory, and infectious causes. Aside from speech delay, he has a normal neurologic exam.
Angela Tran, Namrata Patel‐Sanchez
wiley   +1 more source

When manual disimpaction isn't enough: Case report and review of neostigmine's role in refractory constipation management

JPGN Reports, EarlyView.
ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mojdeh Mostafavi, Sarah Lee, Victoria Martin   +2 more
wiley   +1 more source

Synaptic Potentials Mediated via α-Bungarotoxin-Sensitive Nicotinic Acetylcholine Receptors in Rat Hippocampal Interneurons [PDF]

, 1998
Charles J. Frazier, Amber V. Buhler, Jeffrey L. Weiner, Thomas V. Dunwiddie   +3 more
openalex   +1 more source

Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome

JPGN Reports, EarlyView.
Abstract We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi‐system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities.
Katherine (Tusia) Pohoreski, Gary Galante, Kiera Pajunen, Marie‐Anne Brundler, Samarjeet Bhandal, Iwona Wrobel   +5 more
wiley   +1 more source

Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines. [PDF]

Commun Biol
Mitchell EL, Armstrong EB, Viscarra F, Bermudez I, Biggin PC, Goodchild JA, Jones AK.   +6 more
europepmc   +1 more source

Acute Effects of the 5‐Hydroxytryptamine Type 4 Receptor Agonist Mosapride on Pharyngeal Swallowing Physiology in Adults

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The 5‐hydroxytryptamine type 4 receptor agonist mosapride is known to modulate esophageal peristalsis and enhance lower esophageal sphincter compliance. However, its impact on oropharyngeal swallowing physiology remains insufficiently characterized.
Shu‐Wei Liang, Jui‐Sheng Hung, Taher Omari, Ming‐Wun Wong, Wei‐Yi Lei, Tso‐Tsai Liu, Chih‐Hsun Yi, Chien‐Lin Chen   +7 more
wiley   +1 more source