Results 81 to 90 of about 217,964 (360)

Cholesterol modulates acetylcholine receptor diffusion by tuning confinement sojourns and nanocluster stability [PDF]

, 2018
Translational motion of neurotransmitter receptors is key for determining receptor number at the synapse and hence, synaptic efficacy. We combine live-cell STORM superresolution microscopy of nicotinic acetylcholine receptor (nAChR) with single-particle ...
Barrantes, Francisco Jose, Camino, Pablo A., Mosqueira, Alejo   +2 more
core   +2 more sources

Acetylcholine receptors are not functionally independent

Biophysical Journal, 1986
Analysis of current recordings from acetylcholine-activated channels has largely rested so far on the hypothesis of independence, which states that the opening of one channel does not influence that of its neighbors. We have submitted this assumption to several tests, using as experimental material single channel currents from rat myotubes.
Edouard Yeramian, A. Trautmann, Pierre Claverie   +2 more
openaire   +3 more sources

Conformation of acetylcholine bound to the nicotinic acetylcholine receptor. [PDF]

Proceedings of the National Academy of Sciences, 1988
We report here the biologically active conformation of acetylcholine when bound to the high-affinity state of the receptor from Torpedo californica. The acetylcholine conformation was determined in the free and bound states by proton NMR two-dimensional nuclear Overhauser effects. In agreement with x-ray crystallographic data, acetylcholine in solution
Tetsuo Yamane, Ronald W. Behling, Gil Navon, Lynn W. Jelinski   +3 more
openaire   +3 more sources

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]

, 2009
Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen, Fuchs, Paul A., Katz, Eleonora   +2 more
core   +1 more source

Toward Advancement of Fabrication Techniques of Neuromorphic Computing Devices Based on 2D Materials

Advanced Materials Technologies, EarlyView.
This review highlights emerging fabrication techniques of 2D material‐based neuromorphic devices, emphasizing proximity vapor transfer for bioinspired optoelectronic applications. Abstract The growing necessity for power‐efficient and cognitive computation mechanisms has driven progress in neuromorphic computing which seeks to imitate the synaptic ...
Shubham Umeshkumar Gupta, Malkeshkumar Patel, Naveen Kumar, László Pohl, Min‐Joon Park, Sung‐Min Youn, Chaewhan Jeong, Joondong Kim   +7 more
wiley   +1 more source

Functional validation of novel levamisole resistance marker S168T in Haemonchus contortus

International Journal for Parasitology: Drugs and Drug Resistance
Recently, a S168T variant in the acetylcholine receptor subunit ACR-8 was associated with levamisole resistance in the parasitic helminth Haemonchus contortus.
Alistair Antonopoulos, Claude L. Charvet, Kirsty Maitland, Stephen R. Doyle, Cédric Neveu, Roz Laing   +5 more
doaj   +1 more source

Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse. [PDF]

, 2019
Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the central and peripheral nervous system (CNS and PNS, respectively), and spinal cord.
Broide, Ron S, Chen, Yling, Leslie, Frances M, Winzer-Serhan, Ursula H   +3 more
core   +1 more source

New strategic insights into managing fungal biofilms [PDF]

, 2015
Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa, Borgo, Francesca, Morace, Giulia, Nile, Christopher, Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann   +6 more
core   +4 more sources

Structure and function of an acetylcholine receptor

Biophysical Journal, 1982
Structural analysis of an acetylcholine receptor from Torpedo californica leads to a three-dimensional model in which a "monomeric" receptor is shown to contain subunits arranged around a central ionophoretic channel, which in turn traverses the entire 110 A length of the molecule.
Robert H. Fairclough, Joerg Kistler, R. A. Lalancette, Robert M. Stroud, Michael W. Klymkowsky   +4 more
openaire   +3 more sources