Results 81 to 90 of about 116,451 (242)

Acetylcholine-modulated plasticity in reward-driven navigation: a computational study [PDF]

arXiv, 2017
Neuromodulation plays a fundamental role in the acquisition of new behaviours. Our experimental findings show that, whereas acetylcholine biases hippocampal synaptic plasticity towards depression, the subsequent application of dopamine can retroactively convert depression into potentiation.
arxiv  

Acetylcholine Receptors of Insects

, 1980
Publisher Summary Insects have provided material well suited to the investigation of CNS acetylcholine receptors. The central nervous tissues of these organisms have proved amenable to both radiolabelled- ligand-binding studies and single-cell electrophysiology of identifiable neurones. Binding studies have resulted in the characterization in vitro
openaire   +2 more sources

The Haemonchus contortus LGC-39 subunit is a novel subtype of an acetylcholine-gated chloride channel

International Journal for Parasitology: Drugs and Drug Resistance, 2023
The nematode genome exhibits a vast array of Cys-loop receptors that are activated by a diverse set of neurotransmitters and anthelmintic drugs such as ivermectin and levamisole.
Sarah Habibi, Kristen Nazareth, Jennifer Nichols, Sierra Varley, Sean G. Forrester   +4 more
doaj  

Structure and dynamics of dynorphin peptide and its receptor [PDF]

arXiv, 2019
Dynorphin is a neuropeptide involved in pain, addiction and mood regulation. It exerts its activity by binding to the kappa opioid receptor (KOP) which belongs to the large family of G-protein coupled receptors. The dynorphin peptide was discovered in 1975, while its receptor was cloned in 1993.
arxiv  

Functional validation of novel levamisole resistance marker S168T in Haemonchus contortus

International Journal for Parasitology: Drugs and Drug Resistance
Recently, a S168T variant in the acetylcholine receptor subunit ACR-8 was associated with levamisole resistance in the parasitic helminth Haemonchus contortus.
Alistair Antonopoulos, Claude L. Charvet, Kirsty Maitland, Stephen R. Doyle, Cédric Neveu, Roz Laing   +5 more
doaj  

Alpha5 nicotine acetylcholine receptor subunit promotes intrahepatic cholangiocarcinoma metastasis

Signal Transduction and Targeted Therapy
Neurotransmitter-initiated signaling pathway were reported to play an important role in regulating the malignant phenotype of tumor cells. Cancer cells could exhibit a “neural addiction” property and build up local nerve networks to achieve an enhanced ...
Yan Fu, Keyu Shen, Hao Wang, Shun Wang, Xufeng Wang, Le Zhu, Yan Zheng, Tiantian Zou, Hongfei Ci, Qiongzhu Dong, Lun-Xiu Qin   +10 more
doaj   +1 more source

Localization of acetylcholine receptor in excitable membrane from the electric organ of Torpedo: Evidence for exposure of receptor antigenic sites on both sides of the membrane. [PDF]

, 1978
R Tarrab-Hazdai, Benjamin Geiger, Sara Fuchs, Abraham Amsterdam   +3 more
openalex   +1 more source

Contrary effects of the gut metabolites deoxycholate and butyrate on the acetylcholine-evoked calcium response in an enteroendocrine cell model

Endocrine and Metabolic Science
The interaction of nutrients and bacterial-derived products and their enteroendocrine effects are still enigmatic. We used the human enteroendocrine tumour cell line P-STS isolated from the terminal ileum as cellular sentinel.
Beatrix Pfanzagl, Erika Jensen-Jarolim
doaj  

Affinity labeling of the acetylcholine-receptor.

, 1967
Jean‐Pierre Changeux, Thomas R. Podleski, Leon Wofsy   +2 more
openalex   +1 more source

Electrophysiological properties of the membrane and acetylcholine receptor in developing rat and chick myotubes. [PDF]

, 1975
A K Ritchie, D M Fambrough
openalex   +1 more source