Results 301 to 310 of about 125,133 (347)

Breathing Without Acetylcholinesterase

2004
Acetylcholine (ACh) mediates neurotransmission at the neuromuscular junction and is involved in respiratory control1, notably chemosensitivity2 of central and peripheral origin. The level of ACh at the synaptic cleft and neuromuscular junction is regulated by the enzyme acetylcholinesterase (AChE).
Chatonnet, Fabrice, Boudinot, Eliane, Chatonnet, Arnaud, Champagnat, Jean, Foutz, Arthur   +4 more
openaire   +8 more sources

The thermal inactivation of acetylcholinesterase

Biochimica et Biophysica Acta, 1963
Abstract Thermal inactivation of acetylcholinesterase (Acetylcholine acetyl-hydrolase, EC, 3.1.1.7) from mammalian erythrocytes is accompanied by a decrease in the Michaelis constant K8, while the substrate inhibition constant K32 remains unchanged. The time course involves two first-order processes, suggesting (a) the presence of two enzymes, or (b)
M.H. Coleman, D.D. Eley
openaire   +3 more sources

Molecular Dynamics of Acetylcholinesterase

Accounts of Chemical Research, 2002
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Shen, Tongye, Tai, Kaihsu, Henchman, Richard H., McCammon, J. Andrew   +3 more
openaire   +4 more sources

Toward an Artificial Acetylcholinesterase

Chemistry - A European Journal, 2000
The methanolysis of choline p-nitrophenylcarbonate in chloroform containing 1% methanol is catalyzed with turnover by ditopic receptors 1 and 2, consisting of a calix[6]arene connected to a bicyclic guanidinium by means of a short spacer. The calix[6]arene subunit strongly binds to the trimethylammonium head group through cation-pi interactions ...
CUEVAS F., DI STEFANO, Stefano, MAGRANS J. O., PRADOS P., MANDOLINI, Luigi, DE MENDOZA J.   +5 more
openaire   +4 more sources

Hysteresis of insect acetylcholinesterase

Chemico-Biological Interactions, 2008
Pre-steady-state catalytic properties of insect acetylcholinesterase (AChE, EC 3.1.1.7) were studied with the neutral substrate N-methylindoxylacetate. Kinetics of soluble Apis mellifera and Drosophila melanogaster AChE forms showed lags (v(i)=0) before reaching the steady-state.
Badiou, Alexandra, Froment, M.T., Fournier, Dominique, Masson, P., Belzunces, Luc   +4 more
openaire   +5 more sources

Acetylcholinesterase in the Rabbit Cornea

Archives of Ophthalmology, 1965
There is strong evidence that the acetylcholine system is responsible for the electric currents which propagate impulses in conducting tissues.1,2In the eye, high concentrations of acetylcholine have been reported in the corneal epithelium;3cholinesterase has been demonstrated in various other ocular tissues chemically4and histochemically;5,6and high ...
Anthony Donn, Robert A. Petersen, Keat-Jin Lee   +2 more
openaire   +3 more sources

Activation of acetylcholinesterase by vanadate

Neuropharmacology, 1985
Vanadate activated acetylcholinesterase in rat ventricular strips. This effect of probably due to the action of vanadate (V) form rather than to vanadyl (IV). Vanadate also activated purified acetylcholinesterase from the electric eel and also erythrocytes, suggesting a direct effect upon this enzyme system.
M.D. Aragonés, R.E. Catalán, J.E. Godoy, A.M. Martínez   +3 more
openaire   +3 more sources

Acetylcholinesterase in the human retina

Brain Research, 1987
The distribution of cholinesterase activity in the human retina was evaluated using histochemical methods. The butyrylcholine esterase (BuChE) inhibitor tetraisopropylpyrophosphoramide was used to localize acetylcholinesterase (AChE) activity, the AChE inhibitor BW284c51 was used to localize BuChE activity, and eserine was used to inhibit all ...
Joe G. Hollyfield, James B. Hutchins
openaire   +3 more sources

Acetylcholinesterase inhibitors in MG: To be or not to be?

Muscle & Nerve, 2009
AbstractMyasthenia gravis (MG) is an autoimmune disorder usually caused by antibodies against either the acetylcholine receptor (AChR) or muscle‐specific tyrosine kinase (MuSK) at the neuromuscular junction. Neuromuscular transmission failure results in muscle fatigue and weakness that can be treated symptomatically with acetylcholinesterase inhibitors
Erik Stålberg, Anna Rostedt Punga
openaire   +3 more sources

Acetylcholinesterase in Alzheimer's disease

Mechanisms of Ageing and Development, 2001
Since the discovery of the cholinergic deficit in Alzheimer disease (AD), acetylcholinesterase (AChE) has been widely investigated in tissues involved in the disease. These studies showed modifications in AChE activity and changes in its polymorphism in brain as well as in cerebro-spinal fluid (CSF) and blood.
openaire   +4 more sources