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ACETYLCHOLINESTERASE IN BULL SPERMATOZOA [PDF]

open access: possibleReproduction, 1964
Acetylcholinesterase occurs in the head, midpiece and tail fractions of sonically disrupted bull epididymal spermatozoa. The enzyme exhibits the characteristic substrate concentration optimum; 1\m=.\5X 10-5 m-eserine competitively inhibits the hydrolysis of the acetylcholine.
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Acetylcholinesterase inhibitors in MG: To be or not to be?

Muscle & Nerve, 2009
AbstractMyasthenia gravis (MG) is an autoimmune disorder usually caused by antibodies against either the acetylcholine receptor (AChR) or muscle‐specific tyrosine kinase (MuSK) at the neuromuscular junction. Neuromuscular transmission failure results in muscle fatigue and weakness that can be treated symptomatically with acetylcholinesterase inhibitors
Erik Stålberg, Anna Rostedt Punga
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Isoenzymes of elapid acetylcholinesterases

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1977
Abstract 1. Acetylcholinesterase activity of Naja naja naja, Naja melanoleuca and Bungarus fasciatus venoms is due to mixtures of isoenzymes. 2. Naja melanoleuca venom has two acetylcholinesterase isozymes and both Naja naja naja and Bungarus fasciatus venoms have four acetylcholinesterase isozymes that are resolved by disc gel ...
W.B. Elliott   +2 more
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Inhibition of acetylcholinesterase by anisomycin

Life Sciences, 1976
Abstract The antibiotic anisomycin, an inhibitor of protein synthesis in eucaryotic cells, which blocks long-term memory in mice, is shown to interact with the cholinergic system by inhibiting reversibly the acetylcholinesterase. The inhibition is a competitive one, the inhibition constant K i being 5.0 × 10 −3 for human brain acetylcholinesterase ...
Götz F. Domagk, Ronald Zech
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Acetylcholinesterase in the Rabbit Cornea

Archives of Ophthalmology, 1965
There is strong evidence that the acetylcholine system is responsible for the electric currents which propagate impulses in conducting tissues.1,2In the eye, high concentrations of acetylcholine have been reported in the corneal epithelium;3cholinesterase has been demonstrated in various other ocular tissues chemically4and histochemically;5,6and high ...
Anthony Donn   +2 more
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Acetylcholinesterase in Alzheimer's disease

Mechanisms of Ageing and Development, 2001
Since the discovery of the cholinergic deficit in Alzheimer disease (AD), acetylcholinesterase (AChE) has been widely investigated in tissues involved in the disease. These studies showed modifications in AChE activity and changes in its polymorphism in brain as well as in cerebro-spinal fluid (CSF) and blood.
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Activation of acetylcholinesterase by vanadate

Neuropharmacology, 1985
Vanadate activated acetylcholinesterase in rat ventricular strips. This effect of probably due to the action of vanadate (V) form rather than to vanadyl (IV). Vanadate also activated purified acetylcholinesterase from the electric eel and also erythrocytes, suggesting a direct effect upon this enzyme system.
M.D. Aragonés   +3 more
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Acetylcholinesterase

1987
International ...
Toutant, J.P., Massoulie, J.
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Acetylcholinesterase in the human retina

Brain Research, 1987
The distribution of cholinesterase activity in the human retina was evaluated using histochemical methods. The butyrylcholine esterase (BuChE) inhibitor tetraisopropylpyrophosphoramide was used to localize acetylcholinesterase (AChE) activity, the AChE inhibitor BW284c51 was used to localize BuChE activity, and eserine was used to inhibit all ...
Joe G. Hollyfield, James B. Hutchins
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Autoantibodies to acetylcholinesterase revisited

Journal of the Neurological Sciences, 2000
A sensitive and specific enzyme linked immunosorbent assay (ELISA) utilizing human recombinant acetylcholinesterase has been employed for the detection of human antibodies to human acetylcholinesterase. The method can detect allogenic antibodies to the Yt(a) form of human erythrocyte AChE. Adaptation of this ELISA method allowed the IgG subclass typing
A Strachan   +5 more
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