Results 181 to 190 of about 91,412 (386)
Human Placental Choline Acetyltransferase [PDF]
, 1971 David Morris, Darshan S. Grewaal
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Exploration, EarlyView.Self‐assembled S‐Cu(I)‐S sites were spatially isolated onto a two‐dimensional Ti3C2 surface to produce a structurally well‐defined and highly functional single‐site copper(I) nanomodulator CuNTD, which can induce severe immunogenic cell death through multiple regulatory pathways of synergistic cascade photothermal‐amplified ROS storms, cuproptosis and ...
Yuanyuan Zhang +11 more
wiley +1 more source
Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases.
Molecules and Cells, 2019 Henriette Aksnes, Rasmus Ree, T. Arnesen
semanticscholar +1 more source
Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets
Food Safety and Health, EarlyView.Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar +5 more
wiley +1 more source
Glia, EarlyView.Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj +5 more
wiley +1 more source
Carnitine Acetyltransferase in Nervous Tissue
, 1966 Richard E. McCaman +2 more
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Partial Purification and Properties of
, 1974 Thomas H. Giddings, Edward C. Cantino
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Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
International Journal of Cancer, EarlyView.Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner +3 more
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Enhancer‐dependent gene regulation in space, time, and malignancies
International Journal of Cancer, EarlyView.Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum +2 more
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